Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 308510..309060 Replicon chromosome
Accession NZ_CP070865
Organism Shewanella putrefaciens strain XY07

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JW975_RS01465 Protein ID WP_025008030.1
Coordinates 308510..308809 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JW975_RS01470 Protein ID WP_025008031.1
Coordinates 308818..309060 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW975_RS01440 303778..304344 - 567 WP_025008028.1 XRE family transcriptional regulator -
JW975_RS01445 304508..305695 + 1188 WP_011787676.1 benzoate/H(+) symporter BenE family transporter -
JW975_RS01450 305747..306223 - 477 WP_011787677.1 GNAT family N-acetyltransferase -
JW975_RS01455 306955..307158 + 204 WP_061782969.1 hypothetical protein -
JW975_RS01460 307392..308258 + 867 WP_025008029.1 hypothetical protein -
JW975_RS01465 308510..308809 - 300 WP_025008030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JW975_RS01470 308818..309060 - 243 WP_025008031.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JW975_RS01475 309538..310281 - 744 WP_025008032.1 hypothetical protein -
JW975_RS01480 310313..311572 - 1260 WP_025008033.1 beta-ketoacyl-ACP synthase -
JW975_RS01485 311573..312298 - 726 WP_011918514.1 3-ketoacyl-ACP reductase FabG2 -
JW975_RS01490 312411..312944 - 534 WP_128090195.1 hotdog family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-66)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11571.40 Da        Isoelectric Point: 9.5972

>T194519 WP_025008030.1 NZ_CP070865:c308809-308510 [Shewanella putrefaciens]
MKNKRYKLSKLAQTHLLKIKDYTIQHFSESQWHKYKESLISGLQMLADNPGLGRSCEDIYPNGFYFPIAKHTAYFTKEDD
FILIVAMLGQPQLPQNHLK

Download         Length: 300 bp

>T194519 NZ_CP093548:c208414-207920 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8936.14 Da        Isoelectric Point: 5.0621

>AT194519 WP_025008031.1 NZ_CP070865:c309060-308818 [Shewanella putrefaciens]
VQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNIVDGEDFLNAL

Download         Length: 243 bp

>AT194519 NZ_CP093548:c208704-208411 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References