Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC(toxin) |
| Location | 30009..30637 | Replicon | plasmid unnamed5 |
| Accession | NZ_CP070614 | ||
| Organism | Rhodococcus sp. R79 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | JWS13_RS00140 | Protein ID | WP_206003893.1 |
| Coordinates | 30227..30637 (+) | Length | 137 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | JWS13_RS00135 | Protein ID | WP_206003892.1 |
| Coordinates | 30009..30230 (+) | Length | 74 a.a. |
Genomic Context
Location: 25307..25738 (432 bp)
Type: Others
Protein ID: WP_012687137.1
Type: Others
Protein ID: WP_012687137.1
Location: 25741..26793 (1053 bp)
Type: Others
Protein ID: WP_012687136.1
Type: Others
Protein ID: WP_012687136.1
Location: 29009..29638 (630 bp)
Type: Others
Protein ID: WP_206004214.1
Type: Others
Protein ID: WP_206004214.1
Location: 30009..30230 (222 bp)
Type: Antitoxin
Protein ID: WP_206003892.1
Type: Antitoxin
Protein ID: WP_206003892.1
Location: 30227..30637 (411 bp)
Type: Toxin
Protein ID: WP_206003893.1
Type: Toxin
Protein ID: WP_206003893.1
Location: 33132..34379 (1248 bp)
Type: Others
Protein ID: WP_206003895.1
Type: Others
Protein ID: WP_206003895.1
Location: 34773..35234 (462 bp)
Type: Others
Protein ID: WP_206003896.1
Type: Others
Protein ID: WP_206003896.1
Location: 25142..25225 (84 bp)
Type: Others
Protein ID: Protein_21
Type: Others
Protein ID: Protein_21
Location: 26753..27592 (840 bp)
Type: Others
Protein ID: WP_206003891.1
Type: Others
Protein ID: WP_206003891.1
Location: 31181..32659 (1479 bp)
Type: Others
Protein ID: WP_206003894.1
Type: Others
Protein ID: WP_206003894.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JWS13_RS00110 | 25142..25225 | - | 84 | Protein_21 | zinc-ribbon domain-containing protein | - |
| JWS13_RS00115 | 25307..25738 | + | 432 | WP_012687137.1 | hypothetical protein | - |
| JWS13_RS00120 | 25741..26793 | + | 1053 | WP_012687136.1 | IS3 family transposase | - |
| JWS13_RS00125 | 26753..27592 | - | 840 | WP_206003891.1 | zinc-ribbon domain-containing protein | - |
| JWS13_RS00130 | 29009..29638 | + | 630 | WP_206004214.1 | hypothetical protein | - |
| JWS13_RS00135 | 30009..30230 | + | 222 | WP_206003892.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
| JWS13_RS00140 | 30227..30637 | + | 411 | WP_206003893.1 | PIN domain-containing protein | Toxin |
| JWS13_RS00145 | 31181..32659 | - | 1479 | WP_206003894.1 | plasmid pRiA4b ORF-3 family protein | - |
| JWS13_RS00150 | 33132..34379 | + | 1248 | WP_206003895.1 | zinc-ribbon domain-containing protein | - |
| JWS13_RS00155 | 34773..35234 | + | 462 | WP_206003896.1 | recombinase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..468864 | 468864 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 15072.28 Da Isoelectric Point: 6.4820
>T194509 WP_206003893.1 NZ_CP070614:30227-30637 [Rhodococcus sp. R79]
MSDPTWLIDKSAMVRLGASPDAEQWANRIQRGLVHICTVTLLEVGYSARTAHDLTRVRRTPPLSAMPLEYSTPAIEDRAL
DVQRQLAERGQHRAPSIPDLLIAATAEISNRVVLHLDKDFDLIAAITGQPVERLVT
MSDPTWLIDKSAMVRLGASPDAEQWANRIQRGLVHICTVTLLEVGYSARTAHDLTRVRRTPPLSAMPLEYSTPAIEDRAL
DVQRQLAERGQHRAPSIPDLLIAATAEISNRVVLHLDKDFDLIAAITGQPVERLVT
Download Length: 411 bp
>T194509 NZ_CP093536:c52581-52276 [Ralstonia pseudosolanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGTGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGTGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8349.36 Da Isoelectric Point: 4.5238
>AT194509 WP_206003892.1 NZ_CP070614:30009-30230 [Rhodococcus sp. R79]
MSDVLIRNFPAEDLALLDEHAARLGISRTEYLRRQLQQEARRTITTVSAADLVRFSQDFPDLADDEVMRGAWS
MSDVLIRNFPAEDLALLDEHAARLGISRTEYLRRQLQQEARRTITTVSAADLVRFSQDFPDLADDEVMRGAWS
Download Length: 222 bp
>AT194509 NZ_CP093536:c52805-52578 [Ralstonia pseudosolanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCGGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA
GTGCGCATCGACCGCCTGCAGATGGGCCACCCGGGCGACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA