Detailed information of TA system TA194508

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pezAT/zeta-ParD
• Location: 1040007..1040977
• Replicon: plasmid unnamed1
• Accession: NZ_CP070610
• Organism: Rhodococcus koreensis strain R85

Toxin (Protein)

• Gene name: pezT
• Uniprot ID: -
• Locus tag: JWS14_RS45665
• Protein ID: WP_206016784.1
• Coordinates: 1040007..1040597 (-)
• Length: 197 a.a.

Antitoxin (Protein)

• Gene name: pezA
• Uniprot ID: -
• Locus tag: JWS14_RS45670
• Protein ID: WP_206016785.1
• Coordinates: 1040594..1040977 (-)
• Length: 128 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JWS14_RS45655	1038180..1038548	-	369	WP_206016783.1	DUF2384 domain-containing protein	-
JWS14_RS45660	1038593..1039870	-	1278	Protein_927	hypothetical protein	-
JWS14_RS45665	1040007..1040597	-	591	WP_206016784.1	AAA family ATPase	Toxin
JWS14_RS45670	1040594..1040977	-	384	WP_206016785.1	hypothetical protein	Antitoxin
JWS14_RS45675	1041631..1042635	-	1005	WP_206016786.1	acyl-CoA/acyl-ACP dehydrogenase	-
JWS14_RS45680	1042893..1044203	-	1311	WP_206016787.1	Rep protein	-
JWS14_RS45685	1044583..1044900	-	318	WP_206016788.1	hypothetical protein	-
JWS14_RS45690	1044897..1045391	-	495	WP_206016789.1	hypothetical protein	-
JWS14_RS45695	1045388..1045696	-	309	WP_061699537.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..1241328	1241328

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• ParD-like antitoxin of type II bacterial toxin-antitoxin system (7-106)

Sequences

Toxin

Protein

• Length: 197 a.a.
• Molecular weight: 21507.41 Da
• Isoelectric Point: 7.5788

>T194508 WP_206016784.1 NZ_CP070610:c1040597-1040007 [Rhodococcus koreensis]
VKRLDLVAGCNGAGKSTFVAFTLAPLLPASPLVNADEIATQRWPADPAIHSYEAAEIAAKTRAHLLTLGKSFIAATVFSQ
ASKLELIDQARTHDYTVVLHVLMIPEELAVQRVRCRVQAGGHDVPEHKIRQRYQRIWGLVAQAFPRFDHASVYDNSSSTG
PRIVAQFTDGHLVGEATWPAWTPTELTSHTSRGEHP

Nucleotide

• Length: 591 bp

>T194508 NZ_CP093535:2170452-2171789 [Ralstonia pseudosolanacearum]
ATGGCGCATCCCGAACTGCATCTGTGGATGAACGGCGAGCATGTCGGCATCTGGACCGCCAGCCGCGCCGGCGTGCCGAT
CCTGCGCTATGACGACGGTTGGCTGCGCTCGCCCAACATGCGGCCGCTGTCGCTGTCGCTGCCGATCCCGGCCGGTGTGC
CCGAGCTGCGCGGCCAGGTGGTCGACGACTACTTCGACAACCTGCTGCCCGAGGCCCAGCCCATCCGCGAGCGCGTGCGG
CGCCGCTTCGGCCTCGCCTCCACGGATGCCGCCGAATTGCTGGCCGCCATCGGCCGCGACTGCGTGGGCGCCGTGCAACT
GCTGCCGCCCGGCATGGCCCCCACCGGCTACGACCGCATCGACAGCGAGCCGCTCACCGACAGCCAGGTCGACACGCTGC
TGCGCAACCTCACCGCCACGCCCGCGCTGGGCGAGGACGCCGGCGACCCCGACGCCTTCCGCATCTCCATTGCCGGCGCG
CAGGAGAAAACCGCCCTGCTGCGCATCGGCGATGCCTGGCACCGGCCGCTGGGCGCCACGCCCACCACGCACATCCTCAA
GCTGCCGCTGGGGCTGATCGGCAACATCCGCGCCGACATGCAGGACTCGGTCGACAACGAATGGCTGTGCGCGCAGCTGC
TGGCGGCCTGGGGGCTGGAGGTGGCGCGCACCGAGATCGCCCGCTTCGGCACCAGCAAAGTGCTGGCGGTCGAGCGCTTC
GACCGTCGCTGGATGCCGGGCAACGCCTGGATCGCGCGCCTGCCGCAGGAAGACTTCTGCCAGGCCACCGGCACGCCCGC
GCACCGCAAATACGAAAACGACGGCGGCCCCGGCATGCGCGCCTGCCTCGACCTGCTGTCCGCGTCCGAACACGCCATCG
ACGACAAGCGCCGCTTCGTGCTGGCGCAACTTGCCTTCTGGCTGCTGGCCGCCACCGACGGGCACGCGAAGAACTTCTCG
CTGGCGATCGGGCGCGGCGGGCGCTTCCGCATGACGCCGCTGTATGACGTGCTCTCGGTCTGGCCGATCATGGGCGACGG
GCCGAACCAGCTGTCGCCCTATCGCGCGCGGCTGGCGATGGCCCTGCGCGGCAAGAACGCGCATGCGCGGCTGGCCGACA
TCCACGTGCGCCACTGGCAGGCGCTGGCGGCGCAATCCGGCGTGCCGGACGCGTTCGCCGGCATGCAGGCGCTGGTCGAG
CGCGTGCCGGCGGGTCTCGAGCGGGTCGAGGCGATCCTGCCGCCCGACTTCTCGGGCCGGGTCTGGAGCAGCGTGCGCAC
CGGCGTGCTCGCGCAGGCCGAGCGCTTTCTCAACGAACTGGCGTCCGTCACCCCATGA

Antitoxin

Protein

• Length: 128 a.a.
• Molecular weight: 13710.21 Da
• Isoelectric Point: 4.9627

>AT194508 WP_206016785.1 NZ_CP070610:c1040977-1040594 [Rhodococcus koreensis]
MHSTGDKVTRLAADLVASAMAEGERQHRTGRQQLEHWARVGRAVSSRQTAARRRVEDALAGRLPLGELGPEEGTVFNAEI
NAAIEEQLATTDYGSTLAAQGITTVALSEDGQIIEYRPDGTRTILPE

Nucleotide

• Length: 384 bp

>AT194508 NZ_CP093535:2170194-2170448 [Ralstonia pseudosolanacearum]
ATGGAGTCCCTGCTCTCCTCGGCGCCGCAGCTGTCGGCGCATCTGAAATCGTTGCGCAAGGCGCGCGGACTCACGCAGGC
CCAGTTGGGCGCACTGCTGGGCGTCAGCCAGAACCGCATCGCCGACATCGAAAAAGACCCGGGCGCGGTCGGCTTCGAGC
AGTTACTGCGCATCCTGCACGCGCTCGGCGCGCAGTTGACGCTGCGCACGTCCGCGCCCGCCGGCACCCCCTCCGCCGCG
CCCGCCGACTGGTAA