194506

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 8898719..8899284 Replicon chromosome
Accession NZ_CP070609
Organism Rhodococcus koreensis strain R85

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag JWS14_RS40585 Protein ID WP_206015806.1
Coordinates 8898928..8899284 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag JWS14_RS40580 Protein ID WP_095864309.1
Coordinates 8898719..8898931 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JWS14_RS40555 8894428..8896513 + 2086 Protein_8045 AAA family ATPase -
JWS14_RS40560 8896556..8896909 + 354 WP_206015805.1 hypothetical protein -
JWS14_RS40565 8896906..8897988 + 1083 Protein_8047 ParA family protein -
JWS14_RS40570 8897988..8898260 + 273 Protein_8048 VapC toxin family PIN domain ribonuclease -
JWS14_RS40575 8898496..8898711 + 216 WP_095864308.1 hypothetical protein -
JWS14_RS40580 8898719..8898931 + 213 WP_095864309.1 ribbon-helix-helix domain-containing protein Antitoxin
JWS14_RS40585 8898928..8899284 + 357 WP_206015806.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
JWS14_RS40590 8899608..8900924 - 1317 WP_206015807.1 patatin-like phospholipase family protein -
JWS14_RS40595 8901585..8901842 + 258 WP_206015808.1 hypothetical protein -
JWS14_RS40600 8901894..8902235 + 342 WP_206015809.1 type II toxin-antitoxin system RelE/ParE family toxin -
JWS14_RS40605 8902235..8902516 + 282 WP_072950595.1 helix-turn-helix domain-containing protein -
JWS14_RS40610 8903433..8903651 + 219 WP_095864313.1 hypothetical protein -
JWS14_RS40615 8903826..8903972 + 147 WP_179377730.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-114)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-40)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12900.60 Da        Isoelectric Point: 10.2781

>T194506 WP_206015806.1 NZ_CP070609:8898928-8899284 [Rhodococcus koreensis]
MIRRGQVHWVDLDPAQGSEAAKRRPAVVVSNDRANATAERLGKGVVTVVPLTSNTAHVFAFQVLVDPDESGMPRESKAQA
EQVRSVSVRRLDGDPVGKLSTRTRTALDEALRLHLDLH

Download         Length: 357 bp

>T194506 NZ_CP093533:21163-21435 [Shinella zoogloeoides]
GTGCGCGACCCGTCCTATTCCGGCCAGTTCCGCCGCGACGTGAAGCGGGCGGAGAAGCGCGGTAAGGACATGGCGAAGCT
GCGCCATGTCCTGCAATTGTTGATCGAGGAAGCACCGCTGCCGGCGCGGTTGCGGGACCATCCTTTGAAAAGCAACTGGA
TCGGCTATCGCGATCTCCACATAGAATCGGATTGGCTGCTGATCTATAAGGTTGACGCCACCAGCGTCCATTTCGAGCGG
ACCGGCACTCATTCTGATTTGTTCCGCGAGTAG

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7588.29 Da        Isoelectric Point: 4.0054

>AT194506 WP_095864309.1 NZ_CP070609:8898719-8898931 [Rhodococcus koreensis]
MTTRFTISLPDEDARVLDAYVRDHGLGGRSAGIRAAVRMLGEVGLERDYAAAFVEGGVDDDWDVTSADEE

Download         Length: 213 bp

>AT194506 NZ_CP093533:20902-21162 [Shinella zoogloeoides]
ATGAGAGTCGATTCCGTAGTGCGCGCGCGCGTCGATGCCGAGACGAAGGATAGTGCCACCAAGGCGCTCGCGGAGATGGG
GCTTTCCGTTTCCGACTATATCCGTATGGCCCTGGTCCGGGTTGCTCGTGACAAGGCCATTCCCTTCCCGGTGAAGGTGC
CGAACGCGGAAACCATAGCGGCTATGGAGAAGACGGCGCGCGGCGAGGACGTTCACAAGGCCAAGGACGCGGGCGACCTG
TTCAAGCAGTTGGGTATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References