Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4657144..4657289 Replicon chromosome
Accession NZ_CP070602
Organism Klebsiella pneumoniae strain KPA9853

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4657180..4657282 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4657144..4657289 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW307_RS23540 4652274..4654334 + 2061 WP_004151449.1 oligopeptidase B -
JW307_RS23545 4654338..4654997 - 660 WP_002911407.1 exodeoxyribonuclease X -
JW307_RS23550 4655076..4655306 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JW307_RS23555 4655419..4655793 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JW307_RS23560 4655797..4656666 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
JW307_RS23565 4656683..4657021 + 339 WP_002911404.1 YebY family protein -
- 4657144..4657289 - 146 - - Antitoxin
- 4657180..4657282 + 103 - - Toxin
JW307_RS23570 4657657..4657800 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JW307_RS23575 4657905..4658873 - 969 WP_004151446.1 VirK/YbjX family protein -
JW307_RS23580 4659030..4659683 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
JW307_RS23585 4659680..4659871 - 192 WP_002911395.1 YebW family protein -
JW307_RS23590 4659969..4660208 - 240 WP_002911393.1 YebV family protein -
JW307_RS23595 4660324..4661757 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194497 NZ_CP070602:4657180-4657282 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194497 NZ_CP070602:c4657289-4657144 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References