Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966207..1966351 Replicon chromosome
Accession NZ_CP070598
Organism Klebsiella pneumoniae strain KPA4411

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966243..1966345 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966207..1966351 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW306_RS11690 1961337..1963397 + 2061 WP_004151449.1 oligopeptidase B -
JW306_RS11695 1963401..1964060 - 660 WP_002911407.1 exodeoxyribonuclease X -
JW306_RS11700 1964139..1964369 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JW306_RS11705 1964482..1964856 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JW306_RS11710 1964860..1965729 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
JW306_RS11715 1965746..1966084 + 339 WP_002911404.1 YebY family protein -
- 1966207..1966351 - 145 - - Antitoxin
- 1966243..1966345 + 103 - - Toxin
JW306_RS11720 1966478..1966837 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
JW306_RS11725 1966836..1967315 + 480 WP_032419797.1 lysis protein -
JW306_RS11730 1968104..1969609 + 1506 WP_020956680.1 hypothetical protein -
JW306_RS11735 1969859..1970287 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
JW306_RS11740 1970297..1970578 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194472 NZ_CP070598:1966243-1966345 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT194472 NZ_CP070598:c1966351-1966207 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References