Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1940621..1940766 Replicon chromosome
Accession NZ_CP070586
Organism Klebsiella pneumoniae strain KP52813

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1940657..1940759 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1940621..1940766 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW304_RS11790 1935751..1937811 + 2061 WP_004148850.1 oligopeptidase B -
JW304_RS11795 1937815..1938474 - 660 WP_002911407.1 exodeoxyribonuclease X -
JW304_RS11800 1938553..1938783 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JW304_RS11805 1938896..1939270 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JW304_RS11810 1939274..1940143 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JW304_RS11815 1940160..1940498 + 339 WP_002911404.1 YebY family protein -
- 1940621..1940766 - 146 - - Antitoxin
- 1940657..1940759 + 103 - - Toxin
JW304_RS11820 1941134..1941277 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JW304_RS11825 1941382..1942350 - 969 WP_004151446.1 VirK/YbjX family protein -
JW304_RS11830 1942507..1943160 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JW304_RS11835 1943157..1943348 - 192 WP_002911395.1 YebW family protein -
JW304_RS11840 1943446..1943685 - 240 WP_002911393.1 YebV family protein -
JW304_RS11845 1943801..1945234 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194419 NZ_CP070586:1940657-1940759 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194419 NZ_CP070586:c1940766-1940621 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References