Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3349808..3349952 | Replicon | chromosome |
| Accession | NZ_CP070579 | ||
| Organism | Klebsiella pneumoniae strain KP52810 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3349814..3349916 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3349808..3349952 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JW303_RS18465 | 3345581..3345862 | + | 282 | WP_032419786.1 | hypothetical protein | - |
| JW303_RS18470 | 3345872..3346300 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| JW303_RS18475 | 3346550..3348055 | - | 1506 | WP_020956680.1 | hypothetical protein | - |
| JW303_RS18480 | 3348844..3349323 | - | 480 | WP_032419797.1 | lysis protein | - |
| JW303_RS18485 | 3349322..3349681 | + | 360 | WP_077253379.1 | tyrosine-type recombinase/integrase | - |
| - | 3349808..3349952 | + | 145 | - | - | Antitoxin |
| - | 3349814..3349916 | - | 103 | - | - | Toxin |
| JW303_RS18490 | 3350075..3350413 | - | 339 | WP_002911404.1 | YebY family protein | - |
| JW303_RS18495 | 3350430..3351299 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| JW303_RS18500 | 3351303..3351677 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JW303_RS18505 | 3351790..3352020 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JW303_RS18510 | 3352099..3352758 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JW303_RS18515 | 3352762..3354822 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T194399 NZ_CP070579:c3349916-3349814 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT194399 NZ_CP070579:3349808-3349952 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
