Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3158042..3158187 Replicon chromosome
Accession NZ_CP070564
Organism Klebsiella pneumoniae strain KP51069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3158049..3158151 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3158042..3158187 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW299_RS17380 3153574..3155007 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JW299_RS17385 3155123..3155362 + 240 WP_002911393.1 YebV family protein -
JW299_RS17390 3155460..3155651 + 192 WP_002911395.1 YebW family protein -
JW299_RS17395 3155648..3156301 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
JW299_RS17400 3156458..3157426 + 969 WP_004151446.1 VirK/YbjX family protein -
JW299_RS17405 3157531..3157674 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3158042..3158187 + 146 - - Antitoxin
- 3158049..3158151 - 103 - - Toxin
JW299_RS17410 3158310..3158648 - 339 WP_002911404.1 YebY family protein -
JW299_RS17415 3158665..3159534 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
JW299_RS17420 3159538..3159912 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JW299_RS17425 3160025..3160255 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JW299_RS17430 3160334..3160993 + 660 WP_002911407.1 exodeoxyribonuclease X -
JW299_RS17435 3160997..3163057 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194338 NZ_CP070564:c3158151-3158049 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194338 NZ_CP070564:3158042-3158187 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References