Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 209385..209860 Replicon chromosome
Accession NZ_CP070508
Organism Serratia ureilytica strain AM923

Toxin (Protein)


Gene name relE Uniprot ID A0A8B4GM79
Locus tag IHE77_RS00930 Protein ID WP_033645001.1
Coordinates 209585..209860 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IHE77_RS00925 Protein ID WP_223524348.1
Coordinates 209385..209585 (+) Length 67 a.a.

Genomic Context

IHE77_RS00895IHE77_RS00900IHE77_RS00920IHE77_RS00925IHE77_RS00930IHE77_RS00940IHE77_RS00945IHE77_RS00905IHE77_RS00910IHE77_RS00915IHE77_RS00935
Location: 204579..205847 (1269 bp)
Type: Others
Protein ID: WP_033645006.1
Location: 205844..207043 (1200 bp)
Type: Others
Protein ID: WP_033652425.1
Location: 209078..209323 (246 bp)
Type: Others
Protein ID: WP_025304890.1
Location: 209385..209585 (201 bp)
Type: Antitoxin
Protein ID: WP_223524348.1
Location: 209585..209860 (276 bp)
Type: Toxin
Protein ID: WP_033645001.1
Location: 212919..214382 (1464 bp)
Type: Others
Protein ID: WP_033644999.1
Location: 214437..214814 (378 bp)
Type: Others
Protein ID: WP_025304893.1
Location: 207078..207641 (564 bp)
Type: Others
Protein ID: WP_046688053.1
Location: 207722..208156 (435 bp)
Type: Others
Protein ID: WP_046688054.1
Location: 208198..208857 (660 bp)
Type: Others
Protein ID: WP_025304889.1
Location: 209920..212238 (2319 bp)
Type: Others
Protein ID: WP_241440314.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IHE77_RS00895 (IHE77_00895)204579..205847+1269WP_033645006.1glycerol-3-phosphate dehydrogenase subunit GlpB-
IHE77_RS00900 (IHE77_00900)205844..207043+1200WP_033652425.1anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC-
IHE77_RS00905 (IHE77_00905)207078..207641-564WP_046688053.1DcrB family lipoprotein-
IHE77_RS00910 (IHE77_00910)207722..208156-435WP_046688054.1GNAT family N-acetyltransferase-
IHE77_RS00915 (IHE77_00915)208198..208857-660WP_025304889.17-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter-
IHE77_RS00920 (IHE77_00920)209078..209323+246WP_025304890.1sulfurtransferase TusA-
IHE77_RS00925 (IHE77_00925)209385..209585+201WP_223524348.1stability determinantAntitoxin
IHE77_RS00930 (IHE77_00930)209585..209860+276WP_033645001.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
IHE77_RS00935 (IHE77_00935)209920..212238-2319WP_241440314.1zinc/cadmium/mercury/lead-transporting ATPase-
IHE77_RS00940 (IHE77_00940)212919..214382+1464WP_033644999.1serralysin family metalloprotease-
IHE77_RS00945 (IHE77_00945)214437..214814+378WP_025304893.1AprI/Inh family metalloprotease inhibitor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10682.57 Da        Isoelectric Point: 11.2806

>T194226 WP_033645001.1 NZ_CP070508:209585-209860 [Serratia ureilytica]
MLNIEWTRAARQDLAEIVGFIANDNPLAARKMKVLIMEAVTPAARHPRIFRRGRVDGTHEIPLHPHYLLIYQVLETHIRV
LRVLHTRRQYP

Download         Length: 276 bp

>T194226 NZ_CP093391:c4040622-4040314 [Salmonella enterica]
ATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATTGA
TGAACTGCATACTCGCATGGTTATCCCATTGTTTCCTGTGAGCAGATTGGTAAATAACCCAGTTAAGCGCCTCACGCCCA
CTCTGAATGTGGAAGGTAATGACTATCTGGTGATGACTCACGAAATGGCGAGTATCAGGCTTTCGCAGATTGGTGATGAG
GTGATGGACGTTCGTTCCCACAGGCAAACCATCAAAAATGCTCTCGATTTTATCTTTGACGGGTTCTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7526.59 Da        Isoelectric Point: 4.1359

>AT194226 WP_223524348.1 NZ_CP070508:209385-209585 [Serratia ureilytica]
MMSILLLPTVAKMENEEHTQGYERWFLERVQEAMDEPWPGIPHDDVMAEMDAVIAAAEARINAKQA

Download         Length: 201 bp

>AT194226 NZ_CP093391:c4040864-4040625 [Salmonella enterica]
ATGTCGGGTATGAGTGTACGACATAAAAAAACAGTCAGTGTCACGCTGGAACCTGCATTGCTTCAGCAAGCCCGTGATGC
AGGTATTAATCTGTCTGCGGTGCTTACCGCCGCGCTGAAAGAGGAAATCAGTGCCACAGGCGTTGAACGCTGGAAAGCAG
AAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTACTGATGAGCACGGCCTTTTATCGGACGATTACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A8B4GM79

Antitoxin

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Source
ID
Structure
No matching records found

References