Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 62181..62716 Replicon chromosome
Accession NZ_CP070508
Organism Serratia ureilytica strain AM923

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IHE77_RS00280 Protein ID WP_147880991.1
Coordinates 62441..62716 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8G2GBD7
Locus tag IHE77_RS00275 Protein ID WP_033639076.1
Coordinates 62181..62441 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHE77_RS00255 (IHE77_00255) 57500..58150 + 651 WP_033645112.1 DcrB-related protein -
IHE77_RS00260 (IHE77_00260) 58191..58796 + 606 WP_033645111.1 glutathione S-transferase -
IHE77_RS00265 (IHE77_00265) 58866..60260 + 1395 WP_033645110.1 L-seryl-tRNA(Sec) selenium transferase -
IHE77_RS00270 (IHE77_00270) 60257..62098 + 1842 WP_160203879.1 selenocysteine-specific translation elongation factor -
IHE77_RS00275 (IHE77_00275) 62181..62441 + 261 WP_033639076.1 ribbon-helix-helix domain-containing protein Antitoxin
IHE77_RS00280 (IHE77_00280) 62441..62716 + 276 WP_147880991.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IHE77_RS00285 (IHE77_00285) 62728..63639 - 912 WP_033645108.1 LysR family transcriptional regulator -
IHE77_RS00290 (IHE77_00290) 63761..64387 + 627 WP_033645107.1 LysE family translocator -
IHE77_RS00295 (IHE77_00295) 64441..65688 - 1248 WP_033633516.1 MFS transporter -
IHE77_RS00300 (IHE77_00300) 65906..66898 + 993 WP_160203880.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10620.42 Da        Isoelectric Point: 10.3377

>T194225 WP_147880991.1 NZ_CP070508:62441-62716 [Serratia ureilytica]
MELKWTSKALPDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQMQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T194225 NZ_CP093391:3440519-3440737 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9682.01 Da        Isoelectric Point: 4.5317

>AT194225 WP_033639076.1 NZ_CP070508:62181-62441 [Serratia ureilytica]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp

>AT194225 NZ_CP093391:3440117-3440491 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References