Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 3027589..3028136 | Replicon | chromosome |
Accession | NZ_CP070506 | ||
Organism | Pseudomonas sp. SDM007 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | JTY93_RS13305 | Protein ID | WP_205478116.1 |
Coordinates | 3027589..3027864 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | JTY93_RS13310 | Protein ID | WP_205478117.1 |
Coordinates | 3027864..3028136 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JTY93_RS13275 | 3023067..3024173 | + | 1107 | WP_205478111.1 | enoyl-CoA hydratase/isomerase family protein | - |
JTY93_RS13280 | 3024177..3025329 | + | 1153 | Protein_2605 | acyl-CoA dehydrogenase family protein | - |
JTY93_RS13285 | 3025384..3025809 | - | 426 | WP_205478113.1 | hypothetical protein | - |
JTY93_RS13290 | 3026080..3026529 | + | 450 | WP_205478114.1 | SRPBCC family protein | - |
JTY93_RS13295 | 3026696..3027142 | + | 447 | WP_169995498.1 | DUF411 domain-containing protein | - |
JTY93_RS13300 | 3027146..3027577 | + | 432 | WP_205478115.1 | VTT domain-containing protein | - |
JTY93_RS13305 | 3027589..3027864 | - | 276 | WP_205478116.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JTY93_RS13310 | 3027864..3028136 | - | 273 | WP_205478117.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
JTY93_RS13315 | 3028214..3028727 | + | 514 | Protein_2612 | alpha/beta hydrolase | - |
JTY93_RS13320 | 3028754..3029707 | + | 954 | WP_205478118.1 | D-2-hydroxyacid dehydrogenase family protein | - |
JTY93_RS13325 | 3030250..3031813 | + | 1564 | Protein_2614 | glycogen synthase GlgA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10623.07 Da Isoelectric Point: 6.4689
>T194217 WP_205478116.1 NZ_CP070506:c3027864-3027589 [Pseudomonas sp. SDM007]
MELKWTSSALSDISRLYEFLAAVNQSAAAHAVQRLTAAPTTLLANPRIGERLEEFEARDVRRIQIGQYEMRYEIVDSTIY
LLRLWHTREDR
MELKWTSSALSDISRLYEFLAAVNQSAAAHAVQRLTAAPTTLLANPRIGERLEEFEARDVRRIQIGQYEMRYEIVDSTIY
LLRLWHTREDR
Download Length: 276 bp
>T194217 NZ_CP093390:4521773-4522084 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTCTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATAAAGAATGA
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTCTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATAAAGAATGA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10085.37 Da Isoelectric Point: 5.6994
>AT194217 WP_205478117.1 NZ_CP070506:c3028136-3027864 [Pseudomonas sp. SDM007]
MATPGKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVRQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDAPLPVPR
MATPGKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVRQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDAPLPVPR
Download Length: 273 bp
>AT194217 NZ_CP093390:4522081-4522527 [Salmonella enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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