Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3027589..3028136 Replicon chromosome
Accession NZ_CP070506
Organism Pseudomonas sp. SDM007

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JTY93_RS13305 Protein ID WP_205478116.1
Coordinates 3027589..3027864 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JTY93_RS13310 Protein ID WP_205478117.1
Coordinates 3027864..3028136 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JTY93_RS13275 3023067..3024173 + 1107 WP_205478111.1 enoyl-CoA hydratase/isomerase family protein -
JTY93_RS13280 3024177..3025329 + 1153 Protein_2605 acyl-CoA dehydrogenase family protein -
JTY93_RS13285 3025384..3025809 - 426 WP_205478113.1 hypothetical protein -
JTY93_RS13290 3026080..3026529 + 450 WP_205478114.1 SRPBCC family protein -
JTY93_RS13295 3026696..3027142 + 447 WP_169995498.1 DUF411 domain-containing protein -
JTY93_RS13300 3027146..3027577 + 432 WP_205478115.1 VTT domain-containing protein -
JTY93_RS13305 3027589..3027864 - 276 WP_205478116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JTY93_RS13310 3027864..3028136 - 273 WP_205478117.1 ribbon-helix-helix protein, CopG family Antitoxin
JTY93_RS13315 3028214..3028727 + 514 Protein_2612 alpha/beta hydrolase -
JTY93_RS13320 3028754..3029707 + 954 WP_205478118.1 D-2-hydroxyacid dehydrogenase family protein -
JTY93_RS13325 3030250..3031813 + 1564 Protein_2614 glycogen synthase GlgA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10623.07 Da        Isoelectric Point: 6.4689

>T194217 WP_205478116.1 NZ_CP070506:c3027864-3027589 [Pseudomonas sp. SDM007]
MELKWTSSALSDISRLYEFLAAVNQSAAAHAVQRLTAAPTTLLANPRIGERLEEFEARDVRRIQIGQYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T194217 NZ_CP093390:4521773-4522084 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTCTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10085.37 Da        Isoelectric Point: 5.6994

>AT194217 WP_205478117.1 NZ_CP070506:c3028136-3027864 [Pseudomonas sp. SDM007]
MATPGKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVRQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDAPLPVPR

Download         Length: 273 bp

>AT194217 NZ_CP093390:4522081-4522527 [Salmonella enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References