Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 830352..831754 Replicon chromosome
Accession NZ_CP070505
Organism Pseudomonas toyotomiensis strain SM2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JWV26_RS03750 Protein ID WP_206418434.1
Coordinates 831185..831754 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JWV26_RS03745 Protein ID WP_206418433.1
Coordinates 830352..831179 (-) Length 276 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JWV26_RS03730 827258..828163 - 906 WP_074917073.1 hypothetical protein -
JWV26_RS03735 828174..828746 - 573 WP_017675063.1 LemA family protein -
JWV26_RS03740 828937..830274 + 1338 WP_072425840.1 peptidase -
JWV26_RS03745 830352..831179 - 828 WP_206418433.1 helix-turn-helix domain-containing protein Antitoxin
JWV26_RS03750 831185..831754 - 570 WP_206418434.1 GNAT family N-acetyltransferase Toxin
JWV26_RS03755 831960..835448 + 3489 WP_093050021.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(14-146)

Antitoxin

(193-270)


Sequences


Toxin        


Download         Length: 190 a.a.        Molecular weight: 21414.63 Da        Isoelectric Point: 7.2799

>T194212 WP_206418434.1 NZ_CP070505:c831754-831185 [Pseudomonas toyotomiensis]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADMREQRALPFVIRLGDELVGTTRFA
DFMNTLPACEIGWTWLDRGQHGSGLNASIKYLMLKHAFENWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALREAMEAGFNA

Download         Length: 570 bp

>T194212 NZ_CP093390:c4039421-4039113 [Salmonella enterica]
ATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATTGA
TGAACTGCATACTCGCATGGTTATCCCATTGTTTCCTGTGAGCAGATTGGTAAATAACCCAGTTAAGCGCCTCACGCCCA
CTCTGAATGTGGAAGGTAATGACTATCTGGTGATGACTCACGAAATGGCGAGTATCAGGCTTTCGCAGATTGGTGATGAG
GTGATGGACGTTCGTTCCCACAGGCAAACCATCAAAAATGCTCTCGATTTTATCTTTGACGGGTTCTGA

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30814.26 Da        Isoelectric Point: 8.7154

>AT194212 WP_206418433.1 NZ_CP070505:c831179-830352 [Pseudomonas toyotomiensis]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNAYVLGVLQELGLVKAGMPSFAFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLVEPPSLEELAAAVSLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp

>AT194212 NZ_CP093390:c4039663-4039424 [Salmonella enterica]
ATGTCGGGTATGAGTGTACGACATAAAAAAACAGTCAGTGTCACGCTGGAACCTGCATTGCTTCAGCAAGCCCGTGATGC
AGGTATTAATCTGTCTGCGGTGCTTACCGCCGCGCTGAAAGAGGAAATCAGTGCCACAGGCGTTGAACGCTGGAAAGCAG
AAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTACTGATGAGCACGGCCTTTTATCGGACGATTACAGGACGTTTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References