Detailed information of TA system TA194205

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 2880911..2881439
• Replicon: chromosome
• Accession: NZ_CP070503
• Organism: Pseudomonas atacamensis strain SM1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: JWU58_RS13125
• Protein ID: WP_206422125.1
• Coordinates: 2880911..2881201 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A341F4V9
• Locus tag: JWU58_RS13130
• Protein ID: WP_016770738.1
• Coordinates: 2881194..2881439 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JWU58_RS13110	2877382..2878794	+	1413	WP_206422124.1	L-seryl-tRNA(Sec) selenium transferase	-
JWU58_RS13115	2878791..2880707	+	1917	WP_206422181.1	selenocysteine-specific translation elongation factor	-
JWU58_RS13125	2880911..2881201	-	291	WP_206422125.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JWU58_RS13130	2881194..2881439	-	246	WP_016770738.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
JWU58_RS13135	2881782..2882141	-	360	WP_073476221.1	hypothetical protein	-
JWU58_RS13140	2882563..2883858	-	1296	WP_206422126.1	OprD family outer membrane porin	-
JWU58_RS13145	2884051..2885754	-	1704	WP_206422127.1	amidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Antitoxin ParD (8-78)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11032.55 Da
• Isoelectric Point: 6.4510

>T194205 WP_206422125.1 NZ_CP070503:c2881201-2880911 [Pseudomonas atacamensis]
MAEYRLTPAAEADLEAIWTYTAQQWGVDQANRYIDILTASFEQLADRPKTAPACDAIRPGYRRCSVESHVIYFRITAYGI
AIIRILHDRMEAQRNL

Nucleotide

• Length: 291 bp

>T194205 NZ_CP093390:298511-298879 [Salmonella enterica]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCTTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGCACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9354.43 Da
• Isoelectric Point: 7.3193

>AT194205 WP_016770738.1 NZ_CP070503:c2881439-2881194 [Pseudomonas atacamensis]
MATVRKTITVTDQQDHWIKAQIEAGHYTNDSEYIRDLIRREQERNAELETVRAALREGESSGAPRPFDADAFKKRMLRAH
G

Nucleotide

• Length: 246 bp

>AT194205 NZ_CP093390:298293-298514 [Salmonella enterica]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGTGCGGTGACGGGGGGCCCTGTCAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGAAGCTGGCGGATAAATGA

Structures

Antitoxin

• AlphaFold DB: A0A341F4V9