Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4523380..4523927 Replicon chromosome
Accession NZ_CP070499
Organism Natronosporangium hydrolyticum strain DSM 106523

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JQS43_RS20375 Protein ID WP_239675980.1
Coordinates 4523380..4523646 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JQS43_RS20380 Protein ID WP_239675981.1
Coordinates 4523643..4523927 (-) Length 95 a.a.

Genomic Context

JQS43_RS20350JQS43_RS20355JQS43_RS20360JQS43_RS20370JQS43_RS20385JQS43_RS20365JQS43_RS20375JQS43_RS20380JQS43_RS20390JQS43_RS20395JQS43_RS20400JQS43_RS20405
Location: 4518503..4519309 (807 bp)
Type: Others
Protein ID: WP_239675975.1
Location: 4519333..4521282 (1950 bp)
Type: Others
Protein ID: WP_239675976.1
Location: 4521279..4522322 (1044 bp)
Type: Others
Protein ID: WP_239675977.1
Location: 4523018..4523347 (330 bp)
Type: Others
Protein ID: WP_239675979.1
Location: 4524000..4524734 (735 bp)
Type: Others
Protein ID: WP_239675982.1
Location: 4522417..4522839 (423 bp)
Type: Others
Protein ID: WP_239675978.1
Location: 4523380..4523646 (267 bp)
Type: Toxin
Protein ID: WP_239675980.1
Location: 4523643..4523927 (285 bp)
Type: Antitoxin
Protein ID: WP_239675981.1
Location: 4525253..4526338 (1086 bp)
Type: Others
Protein ID: WP_239675983.1
Location: 4526404..4526925 (522 bp)
Type: Others
Protein ID: WP_239675984.1
Location: 4526925..4527215 (291 bp)
Type: Others
Protein ID: WP_239675985.1
Location: 4527218..4527808 (591 bp)
Type: Others
Protein ID: WP_239675986.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JQS43_RS20350 (JQS43_20275)4518503..4519309+807WP_239675975.1hypothetical protein-
JQS43_RS20355 (JQS43_20280)4519333..4521282+1950WP_239675976.1fumarate reductase/succinate dehydrogenase flavoprotein subunit-
JQS43_RS20360 (JQS43_20285)4521279..4522322+1044WP_239675977.1succinate dehydrogenase/fumarate reductase iron-sulfur subunit-
JQS43_RS20365 (JQS43_20290)4522417..4522839-423WP_239675978.1(deoxy)nucleoside triphosphate pyrophosphohydrolase-
JQS43_RS20370 (JQS43_20295)4523018..4523347+330WP_239675979.14a-hydroxytetrahydrobiopterin dehydratase-
JQS43_RS20375 (JQS43_20300)4523380..4523646-267WP_239675980.1type II toxin-antitoxin system RelE/ParE family toxinToxin
JQS43_RS20380 (JQS43_20305)4523643..4523927-285WP_239675981.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
JQS43_RS20385 (JQS43_20310)4524000..4524734+735WP_239675982.1class I SAM-dependent methyltransferase-
JQS43_RS20390 (JQS43_20315)4525253..4526338-1086WP_239675983.1redox-regulated ATPase YchF-
JQS43_RS20395 (JQS43_20320)4526404..4526925-522WP_239675984.1hypothetical protein-
JQS43_RS20400 (JQS43_20325)4526925..4527215-291WP_239675985.1hypothetical protein-
JQS43_RS20405 (JQS43_20330)4527218..4527808-591WP_239675986.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(35-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10353.96 Da        Isoelectric Point: 10.9539

>T194195 WP_239675980.1 NZ_CP070499:c4523646-4523380 [Natronosporangium hydrolyticum]
VTYRIELTRAARRALVKDLPEVAAVACWEFIRGPLSEHPHRVGKALRDQLAGHYSARRGEFRVIYQIYEDRVVVRVVAIR
HRRDAYQR

Download         Length: 267 bp

>T194195 NZ_CP093386:3516369-3516587 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10592.94 Da        Isoelectric Point: 4.5317

>AT194195 WP_239675981.1 NZ_CP070499:c4523927-4523643 [Natronosporangium hydrolyticum]
MTTIPLAEARANLSRLVDEAVRTHERVEVTRKGRRAAVIMSADDYDSIMETLDILSDPELVREIRAATAEAEQGEVFSLE
EVTEEMRAHGRLPR

Download         Length: 285 bp

>AT194195 NZ_CP093386:3515967-3516341 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References