Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3223954..3224591 Replicon chromosome
Accession NZ_CP070499
Organism Natronosporangium hydrolyticum strain DSM 106523

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JQS43_RS14330 Protein ID WP_239674888.1
Coordinates 3224208..3224591 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JQS43_RS14325 Protein ID WP_239674887.1
Coordinates 3223954..3224211 (+) Length 86 a.a.

Genomic Context

JQS43_RS14295JQS43_RS14325JQS43_RS14330JQS43_RS14300JQS43_RS14305JQS43_RS14310JQS43_RS14315JQS43_RS14320JQS43_RS14335JQS43_RS14340JQS43_RS14345JQS43_RS14350JQS43_RS14355JQS43_RS14360JQS43_RS14365
Location: 3219731..3220108 (378 bp)
Type: Others
Protein ID: WP_239674881.1
Location: 3223954..3224211 (258 bp)
Type: Antitoxin
Protein ID: WP_239674887.1
Location: 3224208..3224591 (384 bp)
Type: Toxin
Protein ID: WP_239674888.1
Location: 3220156..3221661 (1506 bp)
Type: Others
Protein ID: WP_239674882.1
Location: 3221836..3222261 (426 bp)
Type: Others
Protein ID: WP_239674883.1
Location: 3222258..3222497 (240 bp)
Type: Others
Protein ID: WP_239674884.1
Location: 3222816..3223025 (210 bp)
Type: Others
Protein ID: WP_239674885.1
Location: 3223311..3223742 (432 bp)
Type: Others
Protein ID: WP_239674886.1
Location: 3224959..3225216 (258 bp)
Type: Others
Protein ID: WP_239674889.1
Location: 3225275..3225511 (237 bp)
Type: Others
Protein ID: WP_239674890.1
Location: 3225511..3225768 (258 bp)
Type: Others
Protein ID: WP_239674891.1
Location: 3225722..3226360 (639 bp)
Type: Others
Protein ID: WP_239674892.1
Location: 3226519..3226983 (465 bp)
Type: Others
Protein ID: WP_239674893.1
Location: 3227129..3227761 (633 bp)
Type: Others
Protein ID: WP_239674894.1
Location: 3227976..3228164 (189 bp)
Type: Others
Protein ID: WP_239674895.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JQS43_RS14295 (JQS43_14225)3219731..3220108+378WP_239674881.1VOC family protein-
JQS43_RS14300 (JQS43_14230)3220156..3221661-1506WP_239674882.1class I SAM-dependent DNA methyltransferase-
JQS43_RS14305 (JQS43_14235)3221836..3222261-426WP_239674883.1type II toxin-antitoxin system VapC family toxin-
JQS43_RS14310 (JQS43_14240)3222258..3222497-240WP_239674884.1antitoxin-
JQS43_RS14315 (JQS43_14245)3222816..3223025-210WP_239674885.1type II toxin-antitoxin system VapB family antitoxin-
JQS43_RS14320 (JQS43_14250)3223311..3223742-432WP_239674886.1type II toxin-antitoxin system VapC family toxin-
JQS43_RS14325 (JQS43_14255)3223954..3224211+258WP_239674887.1CopG family transcriptional regulatorAntitoxin
JQS43_RS14330 (JQS43_14260)3224208..3224591+384WP_239674888.1type II toxin-antitoxin system VapC family toxinToxin
JQS43_RS14335 (JQS43_14265)3224959..3225216-258WP_239674889.1hypothetical protein-
JQS43_RS14340 (JQS43_14270)3225275..3225511-237WP_239674890.1hypothetical protein-
JQS43_RS14345 (JQS43_14275)3225511..3225768-258WP_239674891.1hypothetical protein-
JQS43_RS14350 (JQS43_14280)3225722..3226360-639WP_239674892.1ABC transporter substrate-binding protein-
JQS43_RS14355 (JQS43_14285)3226519..3226983-465WP_239674893.1hypothetical protein-
JQS43_RS14360 (JQS43_14290)3227129..3227761-633WP_239674894.1hypothetical protein-
JQS43_RS14365 (JQS43_14295)3227976..3228164-189WP_239674895.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14053.29 Da        Isoelectric Point: 9.9567

>T194193 WP_239674888.1 NZ_CP070499:3224208-3224591 [Natronosporangium hydrolyticum]
VILIDSDVLIAHLRGVEPARDWLRKARTTGPLAVSVVSIAELTGGMRSAERREVFALLGALRAEPVTELVARRAGEFMRQ
YRRSHNGIGIADYLIAATAELHGQQLATLNVRHFPMFADLRPPFEVP

Download         Length: 384 bp

>T194193 NZ_CP093386:2117534-2117637 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9352.44 Da        Isoelectric Point: 4.3952

>AT194193 WP_239674887.1 NZ_CP070499:3223954-3224211 [Natronosporangium hydrolyticum]
MTRTNIYLEERQTAILDRIAGEEGVSRAEVIRRLIDRALAGRDDDLTADLAAIDESFGALGELDVPARGASDREAHLSRM
WQVAA

Download         Length: 258 bp

>AT194193 NZ_CP093386:c2117639-2117494 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References