Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1808508..1809124 Replicon chromosome
Accession NZ_CP070499
Organism Natronosporangium hydrolyticum strain DSM 106523

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JQS43_RS08200 Protein ID WP_239678458.1
Coordinates 1808732..1809124 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JQS43_RS08195 Protein ID WP_239678457.1
Coordinates 1808508..1808735 (+) Length 76 a.a.

Genomic Context

JQS43_RS08165JQS43_RS08175JQS43_RS08180JQS43_RS26040JQS43_RS08195JQS43_RS08200JQS43_RS08205JQS43_RS08170JQS43_RS08210JQS43_RS08215JQS43_RS08220JQS43_RS08225JQS43_RS08230
Location: 1804275..1804907 (633 bp)
Type: Others
Protein ID: WP_239678453.1
Location: 1805788..1806834 (1047 bp)
Type: Others
Protein ID: WP_239678455.1
Location: 1807321..1807920 (600 bp)
Type: Others
Protein ID: Protein_1603
Location: 1807956..1808408 (453 bp)
Type: Others
Protein ID: WP_275581080.1
Location: 1808508..1808735 (228 bp)
Type: Antitoxin
Protein ID: WP_239678457.1
Location: 1808732..1809124 (393 bp)
Type: Toxin
Protein ID: WP_239678458.1
Location: 1809161..1809574 (414 bp)
Type: Others
Protein ID: WP_239678459.1
Location: 1805006..1805662 (657 bp)
Type: Others
Protein ID: WP_239678454.1
Location: 1809593..1810006 (414 bp)
Type: Others
Protein ID: WP_239678460.1
Location: 1810010..1810222 (213 bp)
Type: Others
Protein ID: WP_239678461.1
Location: 1810372..1812693 (2322 bp)
Type: Others
Protein ID: WP_239678462.1
Location: 1812690..1813370 (681 bp)
Type: Others
Protein ID: WP_239678463.1
Location: 1813414..1813935 (522 bp)
Type: Others
Protein ID: WP_239678464.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JQS43_RS08165 (JQS43_08135)1804275..1804907+633WP_239678453.1class I SAM-dependent methyltransferase-
JQS43_RS08170 (JQS43_08140)1805006..1805662-657WP_239678454.1winged helix-turn-helix transcriptional regulator-
JQS43_RS08175 (JQS43_08145)1805788..1806834+1047WP_239678455.1alpha/beta hydrolase-
JQS43_RS08180 (JQS43_08150)1807321..1807920+600Protein_1603hypothetical protein-
JQS43_RS26040 (JQS43_08155)1807956..1808408+453WP_275581080.1hypothetical protein-
JQS43_RS08195 (JQS43_08160)1808508..1808735+228WP_239678457.1hypothetical proteinAntitoxin
JQS43_RS08200 (JQS43_08165)1808732..1809124+393WP_239678458.1PIN domain-containing proteinToxin
JQS43_RS08205 (JQS43_08170)1809161..1809574+414WP_239678459.1Imm10 family immunity protein-
JQS43_RS08210 (JQS43_08175)1809593..1810006-414WP_239678460.1PIN domain-containing protein-
JQS43_RS08215 (JQS43_08180)1810010..1810222-213WP_239678461.1hypothetical protein-
JQS43_RS08220 (JQS43_08185)1810372..1812693-2322WP_239678462.1hypothetical protein-
JQS43_RS08225 (JQS43_08190)1812690..1813370-681WP_239678463.1ABC transporter ATP-binding protein-
JQS43_RS08230 (JQS43_08195)1813414..1813935-522WP_239678464.1PadR family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14077.97 Da        Isoelectric Point: 6.8434

>T194191 WP_239678458.1 NZ_CP070499:1808732-1809124 [Natronosporangium hydrolyticum]
VTFLLDANVVVALCAADHVHHEVASAWFSQTQEPFATTPITQGSVLRFLLREGVDAANALEVMGSVTGHPRHEFWPGDLP
FTNETLRGVVGHRQVTDAYLANQARRRGGKVATLDKGLVALHADVATLVR

Download         Length: 393 bp

>T194191 NZ_CP093386:850390-850788 [Salmonella enterica]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTTTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8327.43 Da        Isoelectric Point: 4.7824

>AT194191 WP_239678457.1 NZ_CP070499:1808508-1808735 [Natronosporangium hydrolyticum]
MRTTVDLPDDLHQMVTAVARDEGKSMSRAIADLLRRQLAPPAGPPMSTDERTGLRVVRLGRPITSEDVRSLEDEE

Download         Length: 228 bp

>AT194191 NZ_CP093386:850163-850390 [Salmonella enterica]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGCAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References