Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
| Location | 145488..146182 | Replicon | chromosome |
| Accession | NZ_CP070499 | ||
| Organism | Natronosporangium hydrolyticum strain DSM 106523 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | JQS43_RS00695 | Protein ID | WP_239677112.1 |
| Coordinates | 145748..146182 (+) | Length | 145 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | JQS43_RS00690 | Protein ID | WP_239677111.1 |
| Coordinates | 145488..145751 (+) | Length | 88 a.a. |
Genomic Context
Location: 141739..142212 (474 bp)
Type: Others
Protein ID: WP_239677108.1
Type: Others
Protein ID: WP_239677108.1
Location: 142255..143646 (1392 bp)
Type: Others
Protein ID: WP_239677109.1
Type: Others
Protein ID: WP_239677109.1
Location: 143682..145343 (1662 bp)
Type: Others
Protein ID: WP_239677110.1
Type: Others
Protein ID: WP_239677110.1
Location: 145488..145751 (264 bp)
Type: Antitoxin
Protein ID: WP_239677111.1
Type: Antitoxin
Protein ID: WP_239677111.1
Location: 145748..146182 (435 bp)
Type: Toxin
Protein ID: WP_239677112.1
Type: Toxin
Protein ID: WP_239677112.1
Location: 146190..146960 (771 bp)
Type: Others
Protein ID: WP_239677113.1
Type: Others
Protein ID: WP_239677113.1
Location: 146965..148356 (1392 bp)
Type: Others
Protein ID: WP_239677114.1
Type: Others
Protein ID: WP_239677114.1
Location: 148373..149053 (681 bp)
Type: Others
Protein ID: WP_239677115.1
Type: Others
Protein ID: WP_239677115.1
Location: 149118..150374 (1257 bp)
Type: Others
Protein ID: WP_239677116.1
Type: Others
Protein ID: WP_239677116.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JQS43_RS00675 (JQS43_00670) | 141739..142212 | + | 474 | WP_239677108.1 | Lrp/AsnC family transcriptional regulator | - |
| JQS43_RS00680 (JQS43_00675) | 142255..143646 | + | 1392 | WP_239677109.1 | PQQ-binding-like beta-propeller repeat protein | - |
| JQS43_RS00685 (JQS43_00680) | 143682..145343 | + | 1662 | WP_239677110.1 | fumarate hydratase | - |
| JQS43_RS00690 (JQS43_00685) | 145488..145751 | + | 264 | WP_239677111.1 | hypothetical protein | Antitoxin |
| JQS43_RS00695 (JQS43_00690) | 145748..146182 | + | 435 | WP_239677112.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| JQS43_RS00700 (JQS43_00695) | 146190..146960 | + | 771 | WP_239677113.1 | DUF4184 family protein | - |
| JQS43_RS00705 (JQS43_00700) | 146965..148356 | + | 1392 | WP_239677114.1 | class II fumarate hydratase | - |
| JQS43_RS00710 (JQS43_00705) | 148373..149053 | + | 681 | WP_239677115.1 | HAD family hydrolase | - |
| JQS43_RS00715 (JQS43_00710) | 149118..150374 | + | 1257 | WP_239677116.1 | serine--tRNA ligase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 145 a.a. Molecular weight: 15708.99 Da Isoelectric Point: 4.7778
>T194187 WP_239677112.1 NZ_CP070499:145748-146182 [Natronosporangium hydrolyticum]
VIIVDVNLLLYAVITGFAEHQRARAWFEATLNSPTQVVLTAPAVFGFLRIATSPRVMVSPLPVADAVGYIQSWLERPNVE
FRSPGPRHLAIAFDLLARIGTAGNLTTDVQLAAYAIEFDAEICSNDADFGRFPDVRWANPLSPG
VIIVDVNLLLYAVITGFAEHQRARAWFEATLNSPTQVVLTAPAVFGFLRIATSPRVMVSPLPVADAVGYIQSWLERPNVE
FRSPGPRHLAIAFDLLARIGTAGNLTTDVQLAAYAIEFDAEICSNDADFGRFPDVRWANPLSPG
Download Length: 435 bp
>T194187 NZ_CP093386:206681-207166 [Salmonella enterica]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG
Antitoxin
Download Length: 88 a.a. Molecular weight: 9966.21 Da Isoelectric Point: 5.5743
>AT194187 WP_239677111.1 NZ_CP070499:145488-145751 [Natronosporangium hydrolyticum]
MRTTLTLDRDVVQLLEDAIHRERRPMKQVVNDALRQALGPTGTADAEPYHLQPHESALRPGLDLTGFNRLADELEDERIL
ERVRHTS
MRTTLTLDRDVVQLLEDAIHRERRPMKQVVNDALRQALGPTGTADAEPYHLQPHESALRPGLDLTGFNRLADELEDERIL
ERVRHTS
Download Length: 264 bp
>AT194187 NZ_CP093386:206406-206693 [Salmonella enterica]
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA