Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943682..1943827 Replicon chromosome
Accession NZ_CP070464
Organism Klebsiella pneumoniae strain B28906

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943718..1943820 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943682..1943827 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JT748_RS09370 1938812..1940872 + 2061 WP_004148850.1 oligopeptidase B -
JT748_RS09375 1940876..1941535 - 660 WP_134919889.1 exodeoxyribonuclease X -
JT748_RS09380 1941614..1941844 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JT748_RS09385 1941957..1942331 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JT748_RS09390 1942335..1943204 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
JT748_RS09395 1943221..1943559 + 339 WP_002911404.1 YebY family protein -
- 1943682..1943827 - 146 - - Antitoxin
- 1943718..1943820 + 103 - - Toxin
JT748_RS09400 1944195..1944338 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JT748_RS09405 1944443..1945411 - 969 WP_014907334.1 VirK/YbjX family protein -
JT748_RS09410 1945568..1946221 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
JT748_RS09415 1946218..1946409 - 192 WP_002911395.1 YebW family protein -
JT748_RS09420 1946507..1946746 - 240 WP_002911393.1 YebV family protein -
JT748_RS09425 1946862..1948295 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194106 NZ_CP070464:1943718-1943820 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194106 NZ_CP070464:c1943827-1943682 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References