Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1926053..1926198 Replicon chromosome
Accession NZ_CP070425
Organism Klebsiella pneumoniae strain B3824

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1926089..1926191 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1926053..1926198 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JT727_RS09235 1921183..1923243 + 2061 WP_004151449.1 oligopeptidase B -
JT727_RS09240 1923247..1923906 - 660 WP_002911407.1 exodeoxyribonuclease X -
JT727_RS09245 1923985..1924215 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JT727_RS09250 1924328..1924702 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JT727_RS09255 1924706..1925575 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JT727_RS09260 1925592..1925930 + 339 WP_002911404.1 YebY family protein -
- 1926053..1926198 - 146 - - Antitoxin
- 1926089..1926191 + 103 - - Toxin
JT727_RS09265 1926567..1926710 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JT727_RS09270 1926815..1927783 - 969 WP_004151446.1 VirK/YbjX family protein -
JT727_RS09275 1927940..1928593 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JT727_RS09280 1928590..1928781 - 192 WP_002911395.1 YebW family protein -
JT727_RS09285 1928879..1929118 - 240 WP_002911393.1 YebV family protein -
JT727_RS09290 1929234..1930667 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193970 NZ_CP070425:1926089-1926191 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193970 NZ_CP070425:c1926198-1926053 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References