Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1927383..1927528 Replicon chromosome
Accession NZ_CP070410
Organism Klebsiella pneumoniae strain B960

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1927419..1927521 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1927383..1927528 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JT722_RS09240 1922513..1924573 + 2061 WP_004151449.1 oligopeptidase B -
JT722_RS09245 1924577..1925236 - 660 WP_002911407.1 exodeoxyribonuclease X -
JT722_RS09250 1925315..1925545 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JT722_RS09255 1925658..1926032 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JT722_RS09260 1926036..1926905 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JT722_RS09265 1926922..1927260 + 339 WP_002911404.1 YebY family protein -
- 1927383..1927528 - 146 - - Antitoxin
- 1927419..1927521 + 103 - - Toxin
JT722_RS09270 1927897..1928040 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JT722_RS09275 1928145..1929113 - 969 WP_004151446.1 VirK/YbjX family protein -
JT722_RS09280 1929270..1929923 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JT722_RS09285 1929920..1930111 - 192 WP_002911395.1 YebW family protein -
JT722_RS09290 1930209..1930448 - 240 WP_002911393.1 YebV family protein -
JT722_RS09295 1930564..1931997 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193922 NZ_CP070410:1927419-1927521 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193922 NZ_CP070410:c1927528-1927383 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References