Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 5776557..5777693 Replicon chromosome
Accession NZ_CP070356
Organism Pseudomonas sp. PDNC002

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JVX91_RS26025 Protein ID WP_205336931.1
Coordinates 5776557..5777324 (-) Length 256 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JVX91_RS26030 Protein ID WP_205336932.1
Coordinates 5777325..5777693 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JVX91_RS26005 5771756..5772646 + 891 WP_205336928.1 metal-dependent hydrolase -
JVX91_RS26010 5772738..5774084 + 1347 WP_205336929.1 FAD-dependent oxidoreductase -
JVX91_RS26015 5774335..5775699 - 1365 WP_205340104.1 DNA recombination protein RmuC -
JVX91_RS26020 5776271..5776480 - 210 WP_205336930.1 hypothetical protein -
JVX91_RS26025 5776557..5777324 - 768 WP_205336931.1 RES domain-containing protein Toxin
JVX91_RS26030 5777325..5777693 - 369 WP_205336932.1 DUF2384 domain-containing protein Antitoxin
JVX91_RS26035 5777958..5778428 + 471 WP_205336933.1 RcnB family protein -
JVX91_RS26040 5778441..5778878 - 438 WP_205336934.1 hypothetical protein -
JVX91_RS26045 5779004..5779486 + 483 WP_205336935.1 GreA/GreB family elongation factor -
JVX91_RS26050 5779616..5779960 + 345 WP_205336936.1 carboxymuconolactone decarboxylase family protein -
JVX91_RS26055 5780060..5780434 + 375 WP_205336937.1 hypothetical protein -
JVX91_RS26065 5780735..5781445 - 711 WP_038803299.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
JVX91_RS26070 5781475..5782185 - 711 WP_205336938.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(68-211)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-50)


Sequences

Toxin        


Download         Length: 256 a.a.        Molecular weight: 28974.28 Da        Isoelectric Point: 8.9684

>T193907 WP_205336931.1 NZ_CP070356:c5777324-5776557 [Pseudomonas sp. PDNC002]
MSFEAGARLWAEYADSVVAPMRGRLVRLVESQGQVATLQLVDTLEEQALLEELLETSKPRMPIPAESLHYLLKTPFRYPP
LRWGSRFGRRHEPSLFYAALKLETAMAESAYYRLVLWEGMSEPPPSGRILSEHASFEARFQVQKGVRLQLPPFREHERAL
CDPQDYRVTQGLGSAMRDAGIEAFEYRSARCPQGGSNVALFVPSAFTEKRPRNLMPWLCETTSGYVAFKHGQVPDSPRIF
RREKYLVAGKLPFPA

Download         Length: 768 bp

>T193907 NZ_CP093276:4630940-4631158 [Raoultella sp. HC6]
ATGTCTGGTGAACCATTAACCAAAACAGACTATTTGATGCGCTTACGCCGTTGTCAGACAATTGATACGCTGGAACGCGT
AATTGAAAAAAATAAATACGAACTTCCGGACAACGAATTGGCTGTATTTTACTCAGCGGCCGATCACCGTCTTGCCGAAT
TGACCATGAATAAGCTGTACGACAAAATCCCGACGTCGGTGTGGAAATTCATTCGCTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13260.44 Da        Isoelectric Point: 8.6264

>AT193907 WP_205336932.1 NZ_CP070356:c5777693-5777325 [Pseudomonas sp. PDNC002]
MSALLKENPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQGGLRVDSKTGELALLLVRIYRSLFALFGGNL
EDMRHFLRTANHHLGGAPLELMEQVQGLVAVVEYLDAIRGKA

Download         Length: 369 bp

>AT193907 NZ_CP093276:4630539-4630913 [Raoultella sp. HC6]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCACAGCTTCGATTTCTCTGCGAAACCCTGTATCATGATTGCCTTGC
AAACCTGGAAGAGAGCAACCACGGGTGGGTTAATGACCCGACCTCGGCTGTCAATCTTCAGCTTAATGAATTGATCGATC
ACATTGCTACCTTCGCGCTTAATTATAAAATTAAGTACGCTGAGGATAATAAACTGATTGCTCAGCTCGATGAATACCTT
GATGACACTTTCATGTTGTTTAGCAGCTACGGCATTAACAGCGTAGACCTGCAGAAATGGCGTAAATCGGGAAATCGGTT
ATTCCGTTGTTTTGTTAACGCCAGCCGGGAAAATCCGGCAAGTCTTTCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References