Detailed information of TA system TA193907

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 5776557..5777693
• Replicon: chromosome
• Accession: NZ_CP070356
• Organism: Pseudomonas sp. PDNC002

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JVX91_RS26025
• Protein ID: WP_205336931.1
• Coordinates: 5776557..5777324 (-)
• Length: 256 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JVX91_RS26030
• Protein ID: WP_205336932.1
• Coordinates: 5777325..5777693 (-)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JVX91_RS26005	5771756..5772646	+	891	WP_205336928.1	metal-dependent hydrolase	-
JVX91_RS26010	5772738..5774084	+	1347	WP_205336929.1	FAD-dependent oxidoreductase	-
JVX91_RS26015	5774335..5775699	-	1365	WP_205340104.1	DNA recombination protein RmuC	-
JVX91_RS26020	5776271..5776480	-	210	WP_205336930.1	hypothetical protein	-
JVX91_RS26025	5776557..5777324	-	768	WP_205336931.1	RES domain-containing protein	Toxin
JVX91_RS26030	5777325..5777693	-	369	WP_205336932.1	DUF2384 domain-containing protein	Antitoxin
JVX91_RS26035	5777958..5778428	+	471	WP_205336933.1	RcnB family protein	-
JVX91_RS26040	5778441..5778878	-	438	WP_205336934.1	hypothetical protein	-
JVX91_RS26045	5779004..5779486	+	483	WP_205336935.1	GreA/GreB family elongation factor	-
JVX91_RS26050	5779616..5779960	+	345	WP_205336936.1	carboxymuconolactone decarboxylase family protein	-
JVX91_RS26055	5780060..5780434	+	375	WP_205336937.1	hypothetical protein	-
JVX91_RS26065	5780735..5781445	-	711	WP_038803299.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
JVX91_RS26070	5781475..5782185	-	711	WP_205336938.1	MBL fold metallo-hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (68-211)

Antitoxin

• Cro/C1-type helix-turn-helix domain (22-50)

Sequences

Toxin

Protein

• Length: 256 a.a.
• Molecular weight: 28974.28 Da
• Isoelectric Point: 8.9684

>T193907 WP_205336931.1 NZ_CP070356:c5777324-5776557 [Pseudomonas sp. PDNC002]
MSFEAGARLWAEYADSVVAPMRGRLVRLVESQGQVATLQLVDTLEEQALLEELLETSKPRMPIPAESLHYLLKTPFRYPP
LRWGSRFGRRHEPSLFYAALKLETAMAESAYYRLVLWEGMSEPPPSGRILSEHASFEARFQVQKGVRLQLPPFREHERAL
CDPQDYRVTQGLGSAMRDAGIEAFEYRSARCPQGGSNVALFVPSAFTEKRPRNLMPWLCETTSGYVAFKHGQVPDSPRIF
RREKYLVAGKLPFPA

Nucleotide

• Length: 768 bp

>T193907 NZ_CP093276:4630940-4631158 [Raoultella sp. HC6]
ATGTCTGGTGAACCATTAACCAAAACAGACTATTTGATGCGCTTACGCCGTTGTCAGACAATTGATACGCTGGAACGCGT
AATTGAAAAAAATAAATACGAACTTCCGGACAACGAATTGGCTGTATTTTACTCAGCGGCCGATCACCGTCTTGCCGAAT
TGACCATGAATAAGCTGTACGACAAAATCCCGACGTCGGTGTGGAAATTCATTCGCTAA

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13260.44 Da
• Isoelectric Point: 8.6264

>AT193907 WP_205336932.1 NZ_CP070356:c5777693-5777325 [Pseudomonas sp. PDNC002]
MSALLKENPAADAVLAKAVLTAREHLAMTQQELAAIVGVDRSAVSRWKQGGLRVDSKTGELALLLVRIYRSLFALFGGNL
EDMRHFLRTANHHLGGAPLELMEQVQGLVAVVEYLDAIRGKA

Nucleotide

• Length: 369 bp

>AT193907 NZ_CP093276:4630539-4630913 [Raoultella sp. HC6]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCACAGCTTCGATTTCTCTGCGAAACCCTGTATCATGATTGCCTTGC
AAACCTGGAAGAGAGCAACCACGGGTGGGTTAATGACCCGACCTCGGCTGTCAATCTTCAGCTTAATGAATTGATCGATC
ACATTGCTACCTTCGCGCTTAATTATAAAATTAAGTACGCTGAGGATAATAAACTGATTGCTCAGCTCGATGAATACCTT
GATGACACTTTCATGTTGTTTAGCAGCTACGGCATTAACAGCGTAGACCTGCAGAAATGGCGTAAATCGGGAAATCGGTT
ATTCCGTTGTTTTGTTAACGCCAGCCGGGAAAATCCGGCAAGTCTTTCTTGTTAG