Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1252516..1253021 Replicon chromosome
Accession NZ_CP070356
Organism Pseudomonas sp. PDNC002

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JVX91_RS05745 Protein ID WP_205338398.1
Coordinates 1252516..1252797 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag JVX91_RS05750 Protein ID WP_169935257.1
Coordinates 1252794..1253021 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JVX91_RS05720 1248417..1249367 + 951 WP_205338394.1 alpha/beta fold hydrolase -
JVX91_RS05725 1249462..1250469 + 1008 WP_205339942.1 AraC family transcriptional regulator ligand-binding domain-containing protein -
JVX91_RS05730 1250471..1250926 - 456 WP_205338395.1 GNAT family N-acetyltransferase -
JVX91_RS05735 1250970..1251887 - 918 WP_205338396.1 LysR family transcriptional regulator -
JVX91_RS05740 1251985..1252272 + 288 WP_205338397.1 DUF2218 domain-containing protein -
JVX91_RS05745 1252516..1252797 - 282 WP_205338398.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JVX91_RS05750 1252794..1253021 - 228 WP_169935257.1 CopG family ribbon-helix-helix protein Antitoxin
JVX91_RS05755 1253273..1254658 + 1386 WP_205338399.1 sodium:solute symporter -
JVX91_RS05760 1254686..1255642 + 957 WP_205338400.1 agmatinase -
JVX91_RS05765 1255718..1256644 + 927 WP_205338401.1 LysR family transcriptional regulator -
JVX91_RS05770 1256641..1257354 + 714 WP_205338402.1 phytanoyl-CoA dioxygenase family protein -
JVX91_RS05775 1257380..1257781 + 402 WP_205338403.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10317.73 Da        Isoelectric Point: 5.6642

>T193906 WP_205338398.1 NZ_CP070356:c1252797-1252516 [Pseudomonas sp. PDNC002]
MSLQWTHKAAADLDAIYDHYVVLIGPEKALRAIQDIVEQVSPLANLEMSSSGSPSEVPGVRELAVERWPYQAAFRVKGRS
VQILRIDRVDNSG

Download         Length: 282 bp

>T193906 NZ_CP093276:c3075107-3073788 [Raoultella sp. HC6]
ATGGCGACGCTCGTGACGTGGATGAACAATGAACGCGTCGGGGAGCTGGTCAAGCTGGCCAACGGCGCGCATCAGTTCCG
CTACGACCCGCGCTGGCTGCAAAACCCGCGCGCCCGCCCGCTCTCCCTGTCGCTGCCGCTGCAGTTCGGCAACATCACTT
CGGATGCGGTGTTTAACTACTTCGACAACCTGCTGCCCGACAGTCCGCTGGTGCGTGACCGCATTGTTAAGCGCTATCAG
GCCCGCTCGAAGCAGCCCTTCGATCTGCTGGCCGAGGTGGGGCGCGACAGCGTCGGGGCGGTCACTCTTCTGCCCGAGGG
CGCCGCTCCGGCCACCGGTGCCCTGACCTGGGAAGCGCTCGACGACGCCCGGCTTGACGCGCTGCTGACGGCCTACCGTG
CGGATATTCCGCTGGGCATGATTAACGGCCAGGAGGCGTTCAGAATATCGGTCGCCGGTGCCCAGGAGAAAACGGCGCTG
CTGAAGATGGACGACCGCTGGTGCATACCGACGGCAACAACGCCGACGACGCATATTATTAAGCTGCCGATCGGCGAGAT
ACGGCAGCCGGACGCGGTGCTGGATCTCAGCGAAAGCGTCGATAACGAATATCTCTGTCTGGCCCTCGCGCGGGCGCTGG
GCTTTGCCGTGCCGGATGCGGAAATTATCACCACCCGCAGCATCCGGGCGCTGGCCGTTGAGCGCTTTGACCGCCGCTGG
GCGCAGGAAAACACGCGGCTGCTGCGCCTGCCGCAGGAGGATCTATGCCAGGCGTTCGGCATTCCTTCCTCAATGAAGTA
CGAGTCGGACGGCGGGCCGGGGATCGCCAGCATCATGGCGTTTCTGCTCGGCTCCAGCGAGGCGCTGAGGGATCGCGCCG
ATTTTATGAAGTTCATCGTTTTTCAATGGCTGATCGGCGCCACCGACGGTCATGCGAAGAATTTTTCCATTTTCCTGCAG
CCCGGCGGCAGCTACCGTCTGACGCCGTTCTACGACATTATCTCGGCGTTTCCTGTGCTGGGGGGCGCGGGTTTGCATAT
CAGCGACCTTAAGCTGTCGATGAGCCTGAAAGCGTCGAAAGGGCGGAAAACGGAGATTCAGACCATCTATCCGCGCCATT
TCCTCGCCACGGCAAAAGAGGTGGGATTTGCGCAGCAGCAGATGCTGGAGATCCTGCGCTATTTTGCCGATAACCTGCCG
CGGGCGGTCGATGCGGTCAGCGCCTCGCTGCCGGAGGATTTTTCCCCGACGGTTTACCAGGCCATTATCTCGCATACCCT
CAGAAACCATGCCCGCCTGCAGAGCGGGCTAGCGGGTTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8259.21 Da        Isoelectric Point: 5.9478

>AT193906 WP_169935257.1 NZ_CP070356:c1253021-1252794 [Pseudomonas sp. PDNC002]
VTTVVSFRADDSLVAALDQLARATHRDRPYHLRQALAQYLERQSWHVAAIDEGVADADAGHLLEHAAIEAKWGLA

Download         Length: 228 bp

>AT193906 NZ_CP093276:c3075376-3075107 [Raoultella sp. HC6]
ATAACGCCCCCGACGATCTACAGCCCGGCCCAGCTGGCAAACCATATCAAGCTGGTGCGGCAAAAAAACCAGTGGACGCA
AAGCGATCTGGCCCGCCGGATAGGTATTAAGCAGGCGACGATCTCGAACTTCGAAAACCATCCGGACAAAACCACCCTCA
CCACGCTGTTCAAGATTTTACAATCTCTTGAAATGACGATGGTGGTGTGCGAAAAGGGCGCGACGTCGGGTCCTGAGCAA
CAGGATAGCCAACGGGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References