Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | unclassified/Polyketide_cyc2(toxin) |
Location | 730297..730929 | Replicon | chromosome |
Accession | NZ_CP070348 | ||
Organism | Mycolicibacterium boenickei strain PDNC014 |
Toxin (Protein)
Gene name | novel[antitoxin] | Uniprot ID | - |
Locus tag | JVX93_RS03620 | Protein ID | WP_205264629.1 |
Coordinates | 730297..730746 (-) | Length | 150 a.a. |
Antitoxin (Protein)
Gene name | novel[toxin] | Uniprot ID | - |
Locus tag | JVX93_RS03625 | Protein ID | WP_205264630.1 |
Coordinates | 730750..730929 (-) | Length | 60 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JVX93_RS03595 | 726695..726937 | + | 243 | WP_090428755.1 | hypothetical protein | - |
JVX93_RS03600 | 726947..728689 | + | 1743 | WP_090427037.1 | fumarate reductase (quinol) flavoprotein subunit | - |
JVX93_RS03605 | 728691..729434 | + | 744 | WP_205264626.1 | succinate dehydrogenase/fumarate reductase iron-sulfur subunit | - |
JVX93_RS03610 | 729431..729805 | + | 375 | WP_205264627.1 | fumarate reductase subunit C | - |
JVX93_RS03615 | 729867..730226 | + | 360 | WP_205264628.1 | fumarate reductase subunit FrdD | - |
JVX93_RS03620 | 730297..730746 | - | 450 | WP_205264629.1 | SRPBCC family protein | Toxin |
JVX93_RS03625 | 730750..730929 | - | 180 | WP_205264630.1 | antitoxin | Antitoxin |
JVX93_RS03630 | 731000..733375 | - | 2376 | WP_205264631.1 | HAD-IC family P-type ATPase | - |
JVX93_RS03635 | 733436..734542 | - | 1107 | WP_205264632.1 | MBL fold metallo-hydrolase | - |
JVX93_RS03640 | 734544..735278 | - | 735 | WP_090427018.1 | enoyl-CoA hydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 150 a.a. Molecular weight: 16099.72 Da Isoelectric Point: 9.6754
>T193901 WP_205264629.1 NZ_CP070348:c730746-730297 [Mycolicibacterium boenickei]
MAKLSVSVDVPLPPEKAWEYASDLSRYDEWLSIHRAWRSMLPETLEKGTVIDSIVEVKGMLNRVKWTLVNYKPPHSLTLN
GDGRGGVKVKLIGKIAPAAVDGVDGAKVTFDVHLGGPALFGPIGMVVAAALKGDIQQSLNKFKSLYASS
MAKLSVSVDVPLPPEKAWEYASDLSRYDEWLSIHRAWRSMLPETLEKGTVIDSIVEVKGMLNRVKWTLVNYKPPHSLTLN
GDGRGGVKVKLIGKIAPAAVDGVDGAKVTFDVHLGGPALFGPIGMVVAAALKGDIQQSLNKFKSLYASS
Download Length: 450 bp
>T193901 NZ_CP093272:c39489-39007 [Klebsiella oxytoca]
GTGGGACGTATAACCGCGCCCGAGCCGTTATCCAGCGCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGAAGGGTACGA
AGAAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCTACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGTGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGCGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA
GTGGGACGTATAACCGCGCCCGAGCCGTTATCCAGCGCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGAAGGGTACGA
AGAAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCTACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGTGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGCGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA
Antitoxin
Download Length: 60 a.a. Molecular weight: 6392.07 Da Isoelectric Point: 4.4883
>AT193901 WP_205264630.1 NZ_CP070348:c730929-730750 [Mycolicibacterium boenickei]
MGFLDKAKDLLSQNADKVEQAIDKAGDVIDEKTQGKYSGAVDKAQEAAKNAINKEEPQQ
MGFLDKAKDLLSQNADKVEQAIDKAGDVIDEKTQGKYSGAVDKAQEAAKNAINKEEPQQ
Download Length: 180 bp
>AT193901 NZ_CP093272:c39743-39477 [Klebsiella oxytoca]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCCGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTAGAGATTGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGATTCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCCGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTAGAGATTGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGATTCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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