Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapB-relB/VapC-Phd
Location 4153674..4154352 Replicon chromosome
Accession NZ_CP070343
Organism Variovorax sp. PDNC026

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JVX96_RS19400 Protein ID WP_081269505.1
Coordinates 4153674..4154087 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JVX96_RS19405 Protein ID WP_106934468.1
Coordinates 4154095..4154352 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JVX96_RS19380 4150339..4151856 + 1518 WP_106934472.1 efflux transporter outer membrane subunit -
JVX96_RS19385 4151853..4152236 + 384 WP_106934471.1 RidA family protein -
JVX96_RS19390 4152233..4152628 + 396 WP_106934470.1 hypothetical protein -
JVX96_RS19395 4152592..4153677 - 1086 WP_106934469.1 patatin-like phospholipase family protein -
JVX96_RS19400 4153674..4154087 - 414 WP_081269505.1 type II toxin-antitoxin system VapC family toxin Toxin
JVX96_RS19405 4154095..4154352 - 258 WP_106934468.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JVX96_RS19410 4154416..4156791 - 2376 WP_081269503.1 RNA-binding transcriptional accessory protein -
JVX96_RS19415 4156872..4157858 - 987 WP_106934467.1 ATP-binding protein -
JVX96_RS19420 4157867..4158661 - 795 WP_081269501.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-117)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15258.31 Da        Isoelectric Point: 4.7286

>T193899 WP_081269505.1 NZ_CP070343:c4154087-4153674 [Variovorax sp. PDNC026]
MYLLDTNVISELRRPRPHGAVLEWLTPVADSDLHLSAVTLGEIQAGIELTREQDAAKASEIEQWASLVAASYNVLPMDAE
TFRLWAKLMHRSSNTLYEDAMIAATAKQHALTVVTRNVNDFAGFGVEILNPFEYTRA

Download         Length: 414 bp

>T193899 NZ_CP093271:4477750-4477968 [Klebsiella oxytoca]
ATGTCTGATAAAACATTAACCAAAATAGACTATTTGATGCGCTTACGACGTTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAAAATAAATATGAACTTTCTGATAATGAACTGGCGGTATTTTACTCAGCAGCCGATCATCGTCTTGCTGAAC
TGACGATGAATAAACTGTATGACAAGATCCCGCCATCGGTCTGGAAATTCATCCGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9488.07 Da        Isoelectric Point: 11.4778

>AT193899 WP_106934468.1 NZ_CP070343:c4154352-4154095 [Variovorax sp. PDNC026]
MKTWAVQDAKARFSEFLEASLVEGPQMVTKRGAEVAVLVPAAEWRRLHATAKPSLKELLLSADARTEFLVPQRGAARRRS
VTPMR

Download         Length: 258 bp

>AT193899 NZ_CP093271:4477349-4477723 [Klebsiella oxytoca]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTTAATGACCCAACCTCAGCTGTCAATCTTCAGCTTAATGAATTGATCGAGC
ACATTGCCGCGTTCGCACTTAATTATAAAATTAAGTATGCTGAGGATAATAAGCTGGTGACTCAGCTTGACGAATATCTG
GATGACACTTTCGTGTTGTTCAGCAACTACGGCATTAACACTGCAGATCTGCAGAAATGGCGTAAATCAGGCAACAGGTT
ATTCCGCTGCTTTGTGAACGCCAGTCGGGAAAACCCGGCCAGTCTTTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References