Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2205228..2205772 Replicon chromosome
Accession NZ_CP070327
Organism MAG: Ferrovum myxofaciens isolate MI1I

Toxin (Protein)


Gene name relE Uniprot ID A0A859AA89
Locus tag JVY19_RS10935 Protein ID WP_031596929.1
Coordinates 2205228..2205503 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8F3E316
Locus tag JVY19_RS10940 Protein ID WP_031596931.1
Coordinates 2205503..2205772 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JVY19_RS10905 (JVY19_10920) 2200336..2201529 - 1194 WP_051862536.1 outer membrane protein assembly factor BamC -
JVY19_RS10910 (JVY19_10925) 2201591..2202484 - 894 WP_227509491.1 4-hydroxy-tetrahydrodipicolinate synthase -
JVY19_RS10915 (JVY19_10930) 2202629..2203543 + 915 WP_031598116.1 dTDP-4-dehydrorhamnose reductase -
JVY19_RS10920 (JVY19_10935) 2203540..2204097 + 558 WP_031598117.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
JVY19_RS10925 (JVY19_10940) 2204094..2204966 + 873 WP_062188209.1 hypothetical protein -
JVY19_RS10935 (JVY19_10950) 2205228..2205503 - 276 WP_031596929.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JVY19_RS10940 (JVY19_10955) 2205503..2205772 - 270 WP_031596931.1 ribbon-helix-helix protein, CopG family Antitoxin
JVY19_RS10945 (JVY19_10960) 2206072..2206401 - 330 WP_031596933.1 hypothetical protein -
JVY19_RS10950 (JVY19_10965) 2206431..2208401 - 1971 WP_273144246.1 histidine kinase -
JVY19_RS10960 (JVY19_10975) 2208574..2210136 + 1563 WP_031595994.1 murein biosynthesis integral membrane protein MurJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10692.45 Da        Isoelectric Point: 9.8610

>T193832 WP_031596929.1 NZ_CP070327:c2205503-2205228 [Ferrovum myxofaciens]
MELKWTSKGLSDLARLYDFLVPVNKSAATRVVQALAAAPASLLVNPRIGEKLEEFEPREVRRILVGKYEMRYEIRESTIY
MLRLWHTREDR

Download         Length: 276 bp

>T193832 NZ_CP093227:162805-162954 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9916.32 Da        Isoelectric Point: 6.4818

>AT193832 WP_031596931.1 NZ_CP070327:c2205772-2205503 [Ferrovum myxofaciens]
MAHTDTKVLTAHVPLLLAEKVDRLATRLERSRGWIVKQALAAWIDMEEERTRLTHEGLADVDAGRVIDHQAVEAWANSLS
TAQPLPAPR

Download         Length: 270 bp

>AT193832 NZ_CP093227:c162760-162701 [Escherichia coli]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References