Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TscAT/-
Location 7042..7553 Replicon chromosome
Accession NZ_CP070306
Organism Staphylococcus sp. SM9054

Toxin (Protein)


Gene name TscT Uniprot ID -
Locus tag JQN77_RS00055 Protein ID WP_001103943.1
Coordinates 7042..7341 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name TscA Uniprot ID -
Locus tag JQN77_RS00060 Protein ID WP_001058486.1
Coordinates 7344..7553 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQN77_RS00025 2192..2770 - 579 WP_000846292.1 hypothetical protein -
JQN77_RS00030 2782..3123 - 342 WP_001161659.1 hypothetical protein -
JQN77_RS00035 3470..4111 - 642 WP_001836978.1 pathogenicity island protein -
JQN77_RS00040 4113..4385 - 273 WP_001149387.1 hypothetical protein -
JQN77_RS00045 4372..5175 - 804 WP_000148374.1 bifunctional DNA primase/polymerase -
JQN77_RS00050 5351..6967 - 1617 WP_000344761.1 hypothetical protein -
JQN77_RS00055 7042..7341 - 300 WP_001103943.1 DUF1474 family protein Toxin
JQN77_RS00060 7344..7553 - 210 WP_001058486.1 hypothetical protein Antitoxin
JQN77_RS00065 7546..7692 - 147 WP_000784875.1 hypothetical protein -
JQN77_RS00070 7689..8006 - 318 WP_000459698.1 helix-turn-helix domain-containing protein -
JQN77_RS00075 8010..8222 - 213 WP_000794315.1 helix-turn-helix transcriptional regulator -
JQN77_RS00080 8396..9028 + 633 WP_000616253.1 helix-turn-helix transcriptional regulator -
JQN77_RS00085 9037..10209 + 1173 WP_000179352.1 site-specific integrase -
JQN77_RS00090 10278..11894 - 1617 WP_000240645.1 chaperonin GroEL -
JQN77_RS00095 11970..12254 - 285 WP_000917289.1 co-chaperone GroES -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - groEL 468..12254 11786


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF1474

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11795.24 Da        Isoelectric Point: 4.5689

>T193817 WP_001103943.1 NZ_CP070306:c7341-7042 [Staphylococcus sp. SM9054]
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLQVYLKEFDELIQKF
HEIEKASSDVSLATESDDA

Download         Length: 300 bp

>T193817 NZ_CP093226:2045059-2045162 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 8252.31 Da        Isoelectric Point: 4.3718

>AT193817 WP_001058486.1 NZ_CP070306:c7553-7344 [Staphylococcus sp. SM9054]
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE

Download         Length: 210 bp

>AT193817 NZ_CP093226:c2045200-2044929 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References