Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 151607..152142 Replicon plasmid pESA134_2
Accession NZ_CP070286
Organism Escherichia albertii strain Sample 169

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JRC46_RS24845 Protein ID WP_204620377.1
Coordinates 151855..152142 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JRC46_RS24840 Protein ID WP_204620376.1
Coordinates 151607..151858 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRC46_RS24830 (146984) 146984..148150 - 1167 WP_204620374.1 plasmid-partitioning protein SopA -
JRC46_RS24835 (148860) 148860..149609 + 750 WP_204620375.1 replication initiation protein RepE -
JRC46_RS24840 (151607) 151607..151858 + 252 WP_204620376.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JRC46_RS24845 (151855) 151855..152142 + 288 WP_204620377.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JRC46_RS24850 (152150) 152150..152386 + 237 WP_204620378.1 hypothetical protein -
JRC46_RS24855 (152506) 152506..152943 - 438 WP_204620379.1 hypothetical protein -
JRC46_RS24860 (152930) 152930..153562 - 633 WP_204620380.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
JRC46_RS24865 (154079) 154079..154759 + 681 WP_204620381.1 HAD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - espC / espC 1..176494 176494


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11101.10 Da        Isoelectric Point: 10.4701

>T193672 WP_204620377.1 NZ_CP070286:151855-152142 [Escherichia albertii]
MTYTVKFRDDALKEWLKLDKAIQQQFAKKLKKCSENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSDVYQLASERMR

Download         Length: 288 bp

>T193672 NZ_CP093070:98452-98853 [Escherichia coli]
ATGCTCGACACGAATATCTGCTCTTTCATTATGCGTGAACAGCCCGCCGCAGTGATCAAACGTCTGGAGCAGGCGGTGCT
GCGTAACCACCGCATTGTCGTGTCGGCCATCACCTATGCGGAGATGCGTTTCGGCGCCACCGGCCCGAAAGCCTCACCGC
GTCATATTGCGCTGGTTGACGCGTTCTGCGCCCGCCTCGATGCCATTCTGCCCTGGGACCGCGCTGCCGTGGACGCCACC
ACGGAGATTAAAATGGCACTGCGGCTGGCCGGGACGCCAATCGGCCCGAACGACACGGCGATTGCCGGGCACGCCATCGC
TGCCGGGGCGATACTGGTGACGAATAATACAAGAGAGTTTGAGCGGGTGCCTGACCTGGTGCTGGAAGACTGGGTGAAGT
AA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9184.39 Da        Isoelectric Point: 4.0632

>AT193672 WP_204620376.1 NZ_CP070286:151607-151858 [Escherichia albertii]
MPNIILTDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPADLYEKMLDALDDQELVKLVAERSNQQLHDVDLD
SYL

Download         Length: 252 bp

>AT193672 NZ_CP093070:98198-98428 [Escherichia coli]
ATGAGAACCGTATCGATATTTAAAAATGGCAACAACCGCGCCATCCGTCTGCCCCGTGATCTGGATTTTGAGGGGGTGAG
CGAGCTTGAGATCGTCCGCGAAGGAGACAGCATTATATTGCGCCCGGTCCGGCCGACCTGGAGCTCGTTTGCGGCACTCG
AAAAGGCCGACGCAGACTTTATGGCGGAGCGTGAGGACATTGTCAGCGACGAAGGAAGATTTGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References