Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 6324..6859 Replicon plasmid pESA135_2
Accession NZ_CP070283
Organism Escherichia albertii strain Sample 170

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JRC42_RS24050 Protein ID WP_204620377.1
Coordinates 6572..6859 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JRC42_RS24045 Protein ID WP_204620376.1
Coordinates 6324..6575 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRC42_RS24035 (1701) 1701..2867 - 1167 WP_204620374.1 plasmid-partitioning protein SopA -
JRC42_RS24040 (3577) 3577..4326 + 750 WP_204620375.1 replication initiation protein RepE -
JRC42_RS24045 (6324) 6324..6575 + 252 WP_204620376.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
JRC42_RS24050 (6572) 6572..6859 + 288 WP_204620377.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JRC42_RS24055 (6867) 6867..7103 + 237 WP_204620378.1 hypothetical protein -
JRC42_RS24060 (7223) 7223..7660 - 438 WP_204620379.1 hypothetical protein -
JRC42_RS24065 (7647) 7647..8279 - 633 WP_204620380.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
JRC42_RS24070 (8796) 8796..9476 + 681 WP_204620381.1 HAD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - espC / espC 1..176494 176494


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11101.10 Da        Isoelectric Point: 10.4701

>T193631 WP_204620377.1 NZ_CP070283:6572-6859 [Escherichia albertii]
MTYTVKFRDDALKEWLKLDKAIQQQFAKKLKKCSENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSDVYQLASERMR

Download         Length: 288 bp

>T193631 NZ_CP093043:1000816-1001100 [Bartonella krasnovii]
ATGAAAATAACCCCATTTAAACCAGAAGAATATCTTAAAGACATTGAGTCACAGAAAATTTTTCTCAATGAAGCCCTTAA
AACCGGTGATGCCGCCCACATTGCCGATGCTCTTGGTATCGTTGCTCGTGCCCAAAATATGAGTGCCTTAGCAAAAGAAA
CCAATCGCGAACGCAGTGGATTATACCGTTCCTTAAGTAAAACGGGTGACCCAAAGCTTTCTACCTTAGTCGCTGTATTA
TCTGCCCTTAATTTACAACTCTCTGTACAATCTTCTACTTCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9184.39 Da        Isoelectric Point: 4.0632

>AT193631 WP_204620376.1 NZ_CP070283:6324-6575 [Escherichia albertii]
MPNIILTDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPADLYEKMLDALDDQELVKLVAERSNQQLHDVDLD
SYL

Download         Length: 252 bp

>AT193631 NZ_CP093043:1000527-1000835 [Bartonella krasnovii]
ATGATACTCATTCATAAAACAATAGAATTTGATACTTGGCTTAAGAAACTTAAAGATAAAAGCGTTAAGGCTATTATTCT
TCAACGTGTTGTACGCTTAAAACAAGGACTTTTCGGTGATGTTAAATTCTTTCATGGCATAGGGGAATTACGTATCCACT
ATGGTGCTGGTTACAGAATTTATTTTACCCAAAAAGGCTCTGATTTTATCCTTTTGTTATGCGGTGGAGATAAATCAACG
CAGCAAAGAGATATTGAACAAGCGTTAAAATTAAAAGAGGAGTACAGTGATGAAAATAACCCCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References