Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 97637..98172 Replicon plasmid pESA135_1
Accession NZ_CP070282
Organism Escherichia albertii strain Sample 170

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JRC42_RS23840 Protein ID WP_001270421.1
Coordinates 97885..98172 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JRC42_RS23835 Protein ID WP_204620294.1
Coordinates 97637..97888 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRC42_RS23805 (JRC42_23805) 92728..93033 - 306 WP_204620293.1 hypothetical protein -
JRC42_RS23810 (JRC42_23810) 93037..93453 - 417 Protein_100 hypothetical protein -
JRC42_RS23815 (JRC42_23815) 93376..94572 + 1197 Protein_101 translesion error-prone DNA polymerase V subunit UmuC -
JRC42_RS23820 (JRC42_23820) 94713..95675 - 963 WP_147697683.1 ParB family protein -
JRC42_RS23825 (JRC42_23825) 95672..96877 - 1206 WP_000817642.1 AAA family ATPase -
JRC42_RS23830 (JRC42_23830) 97251..97463 + 213 WP_204620323.1 hypothetical protein -
JRC42_RS23835 (JRC42_23835) 97637..97888 + 252 WP_204620294.1 antitoxin Antitoxin
JRC42_RS23840 (JRC42_23840) 97885..98172 + 288 WP_001270421.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JRC42_RS23845 (JRC42_23845) 98174..98299 + 126 Protein_107 IS3 family transposase -
JRC42_RS23850 (JRC42_23850) 98293..98625 - 333 Protein_108 tyrosine-type recombinase/integrase -
JRC42_RS23855 (JRC42_23855) 98732..98863 - 132 Protein_109 serine/threonine protein kinase -
JRC42_RS23860 (JRC42_23860) 98936..99257 + 322 Protein_110 epoxyqueuosine reductase QueH -
JRC42_RS23865 (JRC42_23865) 99499..99876 - 378 WP_204678055.1 hypothetical protein -
JRC42_RS23870 (JRC42_23870) 100031..100249 + 219 Protein_112 IS200/IS605 family transposase -
JRC42_RS25320 100465..100737 + 273 Protein_113 secretion protein EspO -
JRC42_RS23875 (JRC42_23875) 101058..101204 + 147 Protein_114 IS3 family transposase -
JRC42_RS25325 101373..102023 + 651 WP_244259620.1 RIO1 family regulatory kinase/ATPase -
JRC42_RS23885 (JRC42_23885) 102854..103150 - 297 Protein_116 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - exeG / exeE / stcE 1..120691 120691


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11244.27 Da        Isoelectric Point: 10.4703

>T193630 WP_001270421.1 NZ_CP070282:97885-98172 [Escherichia albertii]
MRYQVKFREDALKEWQKLDKTIQQQFAKKLKKCCDNPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDEQLIIAVVAVGK
RERSDVYNLASERMR

Download         Length: 288 bp

>T193630 NZ_CP093043:1000527-1000835 [Bartonella krasnovii]
ATGATACTCATTCATAAAACAATAGAATTTGATACTTGGCTTAAGAAACTTAAAGATAAAAGCGTTAAGGCTATTATTCT
TCAACGTGTTGTACGCTTAAAACAAGGACTTTTCGGTGATGTTAAATTCTTTCATGGCATAGGGGAATTACGTATCCACT
ATGGTGCTGGTTACAGAATTTATTTTACCCAAAAAGGCTCTGATTTTATCCTTTTGTTATGCGGTGGAGATAAATCAACG
CAGCAAAGAGATATTGAACAAGCGTTAAAATTAAAAGAGGAGTACAGTGATGAAAATAACCCCATTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9182.46 Da        Isoelectric Point: 4.2108

>AT193630 WP_204620294.1 NZ_CP070282:97637-97888 [Escherichia albertii]
MPNIILSDTSASVSELKKNPMATVSAGDGFPVAILNRNQTAFYCVPAELYEKMLDALDDQELVKLVAERSNQPLHDVDLD
KYL

Download         Length: 252 bp

>AT193630 NZ_CP093043:1000816-1001100 [Bartonella krasnovii]
ATGAAAATAACCCCATTTAAACCAGAAGAATATCTTAAAGACATTGAGTCACAGAAAATTTTTCTCAATGAAGCCCTTAA
AACCGGTGATGCCGCCCACATTGCCGATGCTCTTGGTATCGTTGCTCGTGCCCAAAATATGAGTGCCTTAGCAAAAGAAA
CCAATCGCGAACGCAGTGGATTATACCGTTCCTTAAGTAAAACGGGTGACCCAAAGCTTTCTACCTTAGTCGCTGTATTA
TCTGCCCTTAATTTACAACTCTCTGTACAATCTTCTACTTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References