Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2142483..2143081 Replicon chromosome
Accession NZ_CP070273
Organism Marinomonas foliarum strain JZW

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JSY38_RS09870 Protein ID WP_205113105.1
Coordinates 2142483..2142785 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JSY38_RS09875 Protein ID WP_205113106.1
Coordinates 2142782..2143081 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JSY38_RS09855 2138553..2139563 - 1011 WP_205113102.1 substrate-binding domain-containing protein -
JSY38_RS09860 2139815..2140762 + 948 WP_205113103.1 diguanylate cyclase -
JSY38_RS09865 2140859..2142157 - 1299 WP_205113104.1 PAS domain S-box protein -
JSY38_RS09870 2142483..2142785 + 303 WP_205113105.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JSY38_RS09875 2142782..2143081 + 300 WP_205113106.1 putative addiction module antidote protein Antitoxin
JSY38_RS09880 2143109..2143711 - 603 WP_205113107.1 DNA-3-methyladenine glycosylase I -
JSY38_RS09885 2143715..2144113 - 399 WP_205113108.1 GFA family protein -
JSY38_RS09890 2144119..2144301 - 183 Protein_1902 GNAT family N-acetyltransferase -
JSY38_RS09895 2144657..2145751 + 1095 WP_205116754.1 ROK family protein -
JSY38_RS09900 2145816..2147951 - 2136 WP_205113109.1 beta-galactosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11667.46 Da        Isoelectric Point: 10.2603

>T193599 WP_205113105.1 NZ_CP070273:2142483-2142785 [Marinomonas foliarum]
MYDIKLTDEFNLWLRQLKDHSTRIRLARRLEKASRGLLGDVKPVGDGLYEMREHFGPGWRMYYVQRGTTLIIMLAGGDKT
TQSRDIELAKQRARKLDEAT

Download         Length: 303 bp

>T193599 NZ_CP093036:1000511-1000819 [Bartonella krasnovii]
ATGATACTCATTCATAAAACAATAGAATTTGATACTTGGCTTAAGAAACTTAAAGATAAAAGCGTTAAGGCTATTATTCT
TCAACGTGTTGTACGCTTAAAACAAGGACTTTTCGGTGATGTTAAATTCTTTCATGGCATAGGGGAATTACGTATCCACT
ATGGTGCTGGTTACAGAATTTATTTTACCCAAAAAGGCTCTGATTTTATCCTTTTGTTATGCGGTGGAGATAAATCAACG
CAGCAAAGAGATATTGAACAAGCGTTAAAATTAAAAGAGGAGTACAGTGATGAAAATAACCCCATTTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11051.71 Da        Isoelectric Point: 7.3176

>AT193599 WP_205113106.1 NZ_CP070273:2142782-2143081 [Marinomonas foliarum]
MTSIKELTNFDMAEQLRTDEDIATYLSMVLKDGDTDELIHALGHIAKARGMTQIAKDSGLGRESLYKALRSGSRPQFDTI
VKVLKSLNFDLKAVIHTQK

Download         Length: 300 bp

>AT193599 NZ_CP093036:1000800-1001084 [Bartonella krasnovii]
ATGAAAATAACCCCATTTAAACCAGAAGAATATCTTAAAGACATTGAGTCACAGAAAATTTTTCTCAATGAAGCCCTTAA
AACCGGTGATGCCGCCCACATTGCCGATGCTCTTGGTATCGTTGCTCGTGCCCAAAATATGAGTGCCTTAGCAAAAGAAA
CCAATCGCGAACGCAGTGGATTATACCGTTCCTTAAGTAAAACGGGTGACCCAAAGCTTTCTACCTTAGTCGCTGTATTA
TCTGCCCTTAATTTACAACTCTCTGTACAATCTTCTACTTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References