Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 488859..490324 Replicon chromosome
Accession NZ_CP070223
Organism Hydrogenophaga sp. YM1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag JNX00_RS02435 Protein ID WP_204743984.1
Coordinates 488859..489722 (-) Length 288 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag JNX00_RS02440 Protein ID WP_062794306.1
Coordinates 489719..490324 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNX00_RS02415 484812..485690 - 879 WP_204743981.1 ParB N-terminal domain-containing protein -
JNX00_RS02420 485687..486598 - 912 WP_204743982.1 ParB/RepB/Spo0J family partition protein -
JNX00_RS02425 486595..488160 - 1566 WP_204743983.1 recombinase family protein -
JNX00_RS02430 488309..488776 - 468 WP_204744986.1 hypothetical protein -
JNX00_RS02435 488859..489722 - 864 WP_204743984.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
JNX00_RS02440 489719..490324 - 606 WP_062794306.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
JNX00_RS02445 490550..491206 + 657 WP_204743985.1 alpha/beta hydrolase -
JNX00_RS02450 491203..492411 + 1209 WP_153169291.1 XRE family transcriptional regulator -
JNX00_RS02455 492428..492676 + 249 WP_020200504.1 hypothetical protein -
JNX00_RS02460 492697..493158 + 462 WP_204743986.1 hypothetical protein -
JNX00_RS02465 493371..494420 + 1050 WP_204743987.1 acyltransferase family protein -
JNX00_RS02470 494465..494920 - 456 WP_070400486.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-263)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 288 a.a.        Molecular weight: 31281.19 Da        Isoelectric Point: 5.7432

>T193514 WP_204743984.1 NZ_CP070223:c489722-488859 [Hydrogenophaga sp. YM1]
MSAATPAVAASVRARLLNVAKAQGVDFNQVLVRFALERILYRLTQSQHADRFLLKGALLFTLWYDMPHRATRDADLLGFG
ASDLESVAQVFRDIAAVPVDDGIVFDPASVTVEEIRKEAGYGGVRVMIAGDLARARCKTQIDVGFGDAVTPAPVDSVYPV
LLEEMPAPRLRAYPTYTVIAEKLHAIALLGMTNSRLKDYFDLSVLLERETLDTDLLAQAIKATFERRGMALPDALPVGLT
DEFAHDASRQALWLAFLKKNELPPEPLAAIVGRLSVALAPALNTVAR

Download         Length: 864 bp

>T193514 NZ_CP093015:1607033-1607902 [Pseudomonas aeruginosa]
ATGAACATGGCGCAGACCCACATCCCCGCCCCGAGCCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGCTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGCGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCCTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCCCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGCCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22241.81 Da        Isoelectric Point: 9.9042

>AT193514 WP_062794306.1 NZ_CP070223:c490324-489719 [Hydrogenophaga sp. YM1]
MLSSTHNQRVLDLASQKGLLRASDLDAISAPRVVLTRLTAAGLLEKVGRGLYRLPDAQVSEFESLGTIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHPPRVDYPPVKMVQFTGDAYSAGIEEVERDGVRLRVYGVAKTVADCFKHRNKIGLD
VALEALKDARARSKASVDDIWRFAKICRVANVMRPYLESVG

Download         Length: 606 bp

>AT193514 NZ_CP093015:1607895-1608728 [Pseudomonas aeruginosa]
ATGGATAAGTCAGACGATTCGCAAGACAAGTACATCGTGCCTGGCCTCGAACGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGGACCGTACCCTGACGGCGCCGGAGTTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAGGCCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGTTGCGCCTGGGCTTC
GAGTACCTGGCCTCGCTGGAGCTGACCGAACTCGGCCAGCCGCTGCTGAACCGCCTGTGCGACGAGATCCGCTACCCCTG
CAACCTGGTGGTGCGCGACGGCCGTTCGATCGTCTACGTGGCCAAGGTCTCGCCGTCCACCCCGCTGAGCAGCTCGGTGA
ACGTCGGGACCCGGTTGCCGGCCCACGCCACGGTGCTCGGCCGCATCCTGCTGCAGGACCTGAGCCTGGGTGAGCTGCGC
GAGCTGTACCCGGAGGAGCAGCTGGAGCAGTTCTCGCCGAACACCCCGCGCAGCGTGCTGGAACTCTTCGACATGGTCCA
GGGCGACCGCCAGCGTGGCTTCGTCCAGGGCGAGGGGTTCTTCGAGGCGAGCATCTCCACCGTTGCGGCGCCGGTACGTG
ATCACAGCGGTCGCGTCATCGCGGCGATGGGGGCGACCATCGCCGCCGGGCATATCGACCCGGAACGCATCGAGGGACTG
GTCAGCCGGGTGCGCAGCAGCGCCGACGAGCTGTCGTACCTGCTCGACTACCGCGCCGACGGCCAGGACAACGTCACCCC
GATCTTCCGGAGTCGCCCGCATGAAACCGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References