Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2122656..2122924 Replicon chromosome
Accession NZ_CP070170
Organism Escherichia coli strain FDAARGOS_1284

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2122784..2122886 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2122656..2122924 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K14_RS09880 2119209..2119871 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6K14_RS09885 2119895..2120551 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
I6K14_RS09890 2120653..2120883 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6K14_RS09895 2121022..2121396 + 375 WP_000168747.1 CopC domain-containing protein YobA -
I6K14_RS09900 2121400..2122272 + 873 WP_087598017.1 copper homeostasis membrane protein CopD -
I6K14_RS09905 2122285..2122626 + 342 WP_001357782.1 YebY family protein -
- 2122656..2122924 - 269 - - Antitoxin
- 2122784..2122886 + 103 - - Toxin
I6K14_RS09910 2123021..2123677 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
I6K14_RS09915 2123678..2123869 - 192 WP_024186842.1 YebW family protein -
I6K14_RS09920 2123974..2124210 - 237 WP_001295499.1 YebV family protein -
I6K14_RS09925 2124329..2125768 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193466 NZ_CP070170:2122784-2122886 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT193466 NZ_CP070170:c2122924-2122656 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References