Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 684482..684627 Replicon chromosome
Accession NZ_CP070169
Organism Klebsiella pneumoniae strain FDAARGOS_1320

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 684518..684620 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 684482..684627 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K50_RS03085 679612..681672 + 2061 WP_032419805.1 oligopeptidase B -
I6K50_RS03090 681676..682335 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6K50_RS03095 682414..682644 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K50_RS03100 682757..683131 + 375 WP_020316569.1 CopC domain-containing protein YobA -
I6K50_RS03105 683135..684004 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I6K50_RS03110 684021..684359 + 339 WP_002911404.1 YebY family protein -
- 684482..684627 - 146 - - Antitoxin
- 684518..684620 + 103 - - Toxin
I6K50_RS03115 684995..685138 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K50_RS03120 685243..686211 - 969 WP_014907334.1 VirK/YbjX family protein -
I6K50_RS03125 686368..687021 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
I6K50_RS03130 687018..687209 - 192 WP_002911395.1 YebW family protein -
I6K50_RS03135 687307..687546 - 240 WP_002911393.1 YebV family protein -
I6K50_RS03140 687662..689095 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193443 NZ_CP070169:684518-684620 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193443 NZ_CP070169:c684627-684482 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References