Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4072746..4072891 Replicon chromosome
Accession NZ_CP070158
Organism Klebsiella pneumoniae strain FDAARGOS_1310

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4072753..4072855 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4072746..4072891 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K40_RS19560 4068277..4069710 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K40_RS19565 4069826..4070065 + 240 WP_002911393.1 YebV family protein -
I6K40_RS19570 4070163..4070354 + 192 WP_002911395.1 YebW family protein -
I6K40_RS19575 4070351..4071004 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
I6K40_RS19580 4071161..4072129 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K40_RS19585 4072234..4072377 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4072746..4072891 + 146 - - Antitoxin
- 4072753..4072855 - 103 - - Toxin
I6K40_RS19590 4073014..4073352 - 339 WP_002911404.1 YebY family protein -
I6K40_RS19595 4073369..4074238 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
I6K40_RS19600 4074242..4074616 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K40_RS19605 4074729..4074959 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K40_RS19610 4075038..4075697 + 660 WP_020324964.1 exodeoxyribonuclease X -
I6K40_RS19615 4075701..4077761 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193404 NZ_CP070158:c4072855-4072753 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193404 NZ_CP070158:4072746-4072891 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References