Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 458096..458367 Replicon chromosome
Accession NZ_CP070152
Organism Escherichia coli strain FDAARGOS_1285

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 458134..458237 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 458096..458367 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K15_RS02990 455253..456692 + 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K15_RS02995 456810..457046 + 237 WP_001295499.1 YebV family protein -
I6K15_RS03000 457151..457342 + 192 WP_001296140.1 YebW family protein -
I6K15_RS03005 457343..457999 - 657 WP_022645801.1 protein-serine/threonine phosphatase -
- 458096..458367 + 272 - - Antitoxin
- 458134..458237 - 104 - - Toxin
I6K15_RS03010 458395..458736 - 342 WP_000976472.1 YebY family protein -
I6K15_RS03015 458749..459621 - 873 WP_022645802.1 copper homeostasis membrane protein CopD -
I6K15_RS03020 459625..459999 - 375 WP_022645803.1 CopC domain-containing protein YobA -
I6K15_RS03025 460138..460368 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I6K15_RS03030 460470..461126 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
I6K15_RS03035 461150..461812 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T193337 NZ_CP070152:c458237-458134 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT193337 NZ_CP070152:458096-458367 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References