Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 1415584..1416403 Replicon chromosome
Accession NZ_CP070144
Organism Klebsiella oxytoca strain FDAARGOS_1331

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag I6K61_RS06645 Protein ID WP_004110819.1
Coordinates 1416146..1416403 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag I6K61_RS06640 Protein ID WP_004099227.1
Coordinates 1415584..1416135 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K61_RS06625 1410913..1412310 + 1398 WP_077257937.1 MFS transporter -
I6K61_RS06630 1412434..1413774 + 1341 WP_024273771.1 carbohydrate porin -
I6K61_RS06635 1413938..1415566 - 1629 WP_049593479.1 SAM-dependent methyltransferase -
I6K61_RS06640 1415584..1416135 - 552 WP_004099227.1 N-acetyltransferase Antitoxin
I6K61_RS06645 1416146..1416403 - 258 WP_004110819.1 YjhX family toxin Toxin
I6K61_RS06650 1416986..1418170 + 1185 WP_049593480.1 mannonate dehydratase -
I6K61_RS06655 1418245..1419720 + 1476 WP_004110817.1 fructuronate reductase -
I6K61_RS06660 1419856..1420632 + 777 WP_017146569.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T193295 WP_004110819.1 NZ_CP070144:c1416403-1416146 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T193295 NZ_CP092844:1045353-1046264 [Burkholderia ambifaria]
ATGAGTGTCATCGACAAACGTGAACGCGACCGCACCGCGGCATTCGCCGCGCTGCTCGGGCAGTTTCCCGAACAGCGCTG
CGCGGCCGGCGCGGCGGGCACGATCGGCTACCGTGAGGCTGGCGCAGGCGAGGCCGGCGCGCAGCATGCGGGCCACGCGC
TGCCCGTCGTGCTGCTGCACGGGATCGGCTCGGGCGCCGCATCGTGGGTGTGCCAGCTCGACACGCTCGGCGCGTCGCGA
CGCGTGCTTGCGTGGGATGCGCCCGGCTACGGCGTGTCGACCCCCGTGCACGACGCGTCGCCGACCGCCGCCGATTACGC
GGCGTCGCTGAATGCGTGGCTCGAGGCACTCGGCATCGAACGCTGCGTGCTGGTCGGGCATTCGCTCGGCGCGATCATCG
CGGGCGGCCTGTGCCGCCTGATGCCCGCGCGGATCGCCGGCCTGCTGCTGATCTCGCCCGCGGGCGGCTACGGCCGTGCG
CCCGCCGAAACGCGCGACACGCGCCGCGACGCGCGCCTCGCGATGCTCGACGAACTCGGTCCGGCCGGGCTCGCCGAGCA
GCGCAGTGGCAACATGCTGTCGGGTTTCGCGAGCGAGGATGCGCGTGCGTGGGTGCGCTGGAACATGGCGCGCATCGTGC
CGGCCGGCTATGCGCAGGCCACGCATCTGCTCGCGAACGCCGATCTCGCGACCGATCTCGCCGGCTTCCGCGGCCGCACG
GCCGTGGCCGTCGGCGCGAACGACGCGATCACGCCGCCCGCCGCGTGCGAGCGGATCGCCGCGGCCGCGCAGGTCGAATT
GCAGGTGATTCCGCAGGCCGGTCATGCCGGCTACGTGGAAGCGCCGGCCGTCTATTCGTCGCTTATCGACACGTTCTGTC
GTCAGTGCGACACGCAGCGAGGCATGGCATGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20246.21 Da        Isoelectric Point: 6.7178

>AT193295 WP_004099227.1 NZ_CP070144:c1416135-1415584 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVADLLNDESAHPRLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGMGVGGLLIQSGIEHLKAMGSLAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGITGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT193295 NZ_CP092844:1046261-1047118 [Burkholderia ambifaria]
ATGAGCGAACCGCTGCAACAACCAGAATCCGACAGCACCAAGGCCGACGCCGGCTACGTGGTGCCGGGCCTCGAACGCGG
GCTGCGGATCCTCGCCGAATTCTCCCCGCGCGAGCCGGTGCTCGGCGCGCCGGAGTTGTCCAAGCGCCTCGGCATTCCGC
GCACGACGGTGTTCCGTCTGCTGCAGACGCTCGAATCGCTCGGCTTTCTCGAGCGGGCGGACAAGGATCGCAACTACAAG
CTGGGCATCGCCGTGCTGCGGCTCGGCTTCGAATACCTGAGCTCGCTGGAGTTGACCGATCTCGGCCTGCCGGTGATCGA
GAGCCTGCGCGACGCGACCGGCTTCACGACGCACATCGTGATTCGCGACGGCCGCGACGTGGTGTTCGTCGCGAAGGCGC
AGTGCCAGTCGCCGGTGTTCAGCGCGATTCGCGTGAACGTCGGCACGCGGCTGCCCGCGCATGCGACGACCCACGGCCAC
GTGCTGATGGGCGACCTGTCGCTGAAGGAGCTGCGTGCGCTGTATCCGGAAGGCACGCTGAGCCGGATGACGAGCGCGAC
GCCGGAAACGGTCGATGCGCTGTACGAAGTGATCCGCGAGGATGCGCTGCGCGGCTACGGCATCAGCAATTCGTCGTTCG
AGCGCGGCATCTCGGTGGTCACGGCGCCGGTGCGCAACGACACGCAGAAGATCGTCGCGTGCATCACGGTGACGGTGCCG
CGGCCGGAGATCGACGAGGCGCTGATCGCCGACGGCCTGTTCGACAAGGTGCAGCGCGCGGCGGCGGAACTGTCGCGGCG
GCTCAATTACCGCTCGGATGACGAGCACACGTTTCTCAAAGCTTTAGGACTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References