Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 28120..28265 Replicon chromosome
Accession NZ_CP070105
Organism Klebsiella pneumoniae strain FDAARGOS_1314

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 28127..28229 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 28120..28265 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K44_RS00115 23653..25086 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K44_RS00120 25202..25441 + 240 WP_002911393.1 YebV family protein -
I6K44_RS00125 25539..25730 + 192 WP_002911395.1 YebW family protein -
I6K44_RS00130 25727..26380 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
I6K44_RS00135 26537..27505 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K44_RS00140 27610..27753 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 28120..28265 + 146 - - Antitoxin
- 28127..28229 - 103 - - Toxin
I6K44_RS00145 28388..28726 - 339 WP_002911404.1 YebY family protein -
I6K44_RS00150 28743..29612 - 870 WP_064172307.1 copper homeostasis membrane protein CopD -
I6K44_RS00155 29616..29990 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K44_RS00160 30103..30333 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K44_RS00165 30412..31071 + 660 WP_021440386.1 exodeoxyribonuclease X -
I6K44_RS00170 31075..33135 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193138 NZ_CP070105:c28229-28127 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193138 NZ_CP070105:28120-28265 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References