Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4565862..4566007 Replicon chromosome
Accession NZ_CP070092
Organism Klebsiella pneumoniae strain FDAARGOS_1316

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4565869..4565971 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4565862..4566007 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K46_RS22110 4561394..4562827 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K46_RS22115 4562943..4563182 + 240 WP_002911393.1 YebV family protein -
I6K46_RS22120 4563280..4563471 + 192 WP_002911395.1 YebW family protein -
I6K46_RS22125 4563468..4564121 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
I6K46_RS22130 4564278..4565246 + 969 WP_014907334.1 VirK/YbjX family protein -
I6K46_RS22135 4565351..4565494 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4565862..4566007 + 146 - - Antitoxin
- 4565869..4565971 - 103 - - Toxin
I6K46_RS22140 4566130..4566468 - 339 WP_002911404.1 YebY family protein -
I6K46_RS22145 4566485..4567354 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I6K46_RS22150 4567358..4567732 - 375 WP_020316569.1 CopC domain-containing protein YobA -
I6K46_RS22155 4567845..4568075 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K46_RS22160 4568154..4568813 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K46_RS22165 4568817..4570877 - 2061 WP_032419805.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193057 NZ_CP070092:c4565971-4565869 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193057 NZ_CP070092:4565862-4566007 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References