Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 340932..341077 Replicon chromosome
Accession NZ_CP070088
Organism Klebsiella pneumoniae strain FDAARGOS_1306

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 340968..341070 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 340932..341077 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K36_RS01625 336062..338122 + 2061 WP_049000289.1 oligopeptidase B -
I6K36_RS01630 338126..338785 - 660 WP_038431281.1 exodeoxyribonuclease X -
I6K36_RS01635 338864..339094 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K36_RS01640 339207..339581 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K36_RS01645 339585..340454 + 870 WP_057774489.1 copper homeostasis membrane protein CopD -
I6K36_RS01650 340471..340809 + 339 WP_002911404.1 YebY family protein -
- 340932..341077 - 146 - - Antitoxin
- 340968..341070 + 103 - - Toxin
I6K36_RS01655 341445..341588 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K36_RS01660 341693..342661 - 969 WP_072158545.1 VirK/YbjX family protein -
I6K36_RS01665 342818..343471 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
I6K36_RS01670 343468..343659 - 192 WP_002911395.1 YebW family protein -
I6K36_RS01675 343757..343996 - 240 WP_002911393.1 YebV family protein -
I6K36_RS01680 344112..345545 - 1434 WP_040236949.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193028 NZ_CP070088:340968-341070 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193028 NZ_CP070088:c341077-340932 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References