Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3798988..3799133 Replicon chromosome
Accession NZ_CP070087
Organism Klebsiella pneumoniae strain FDAARGOS_1328

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3799024..3799126 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3798988..3799133 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K58_RS20325 3794118..3796178 + 2061 WP_004151449.1 oligopeptidase B -
I6K58_RS20330 3796182..3796841 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6K58_RS20335 3796920..3797150 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K58_RS20340 3797263..3797637 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K58_RS20345 3797641..3798510 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
I6K58_RS20350 3798527..3798865 + 339 WP_002911404.1 YebY family protein -
- 3798988..3799133 - 146 - - Antitoxin
- 3799024..3799126 + 103 - - Toxin
I6K58_RS20355 3799501..3799644 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K58_RS20360 3799749..3800717 - 969 WP_004151446.1 VirK/YbjX family protein -
I6K58_RS20365 3800874..3801527 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
I6K58_RS20370 3801524..3801715 - 192 WP_002911395.1 YebW family protein -
I6K58_RS20375 3801813..3802052 - 240 WP_002911393.1 YebV family protein -
I6K58_RS20380 3802168..3803601 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T193018 NZ_CP070087:3799024-3799126 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT193018 NZ_CP070087:c3799133-3798988 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References