Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1021690..1021921 Replicon chromosome
Accession NZ_CP070071
Organism Escherichia coli strain FDAARGOS_1287

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1021818..1021920 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1021690..1021921 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K17_RS05640 1018245..1018907 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6K17_RS05645 1018931..1019587 - 657 WP_000011673.1 carbon-nitrogen hydrolase family protein YobB -
I6K17_RS05650 1019689..1019919 - 231 WP_000916759.1 DNA polymerase III subunit theta -
I6K17_RS05655 1020058..1020432 + 375 WP_000168747.1 CopC domain-containing protein YobA -
I6K17_RS05660 1020436..1021296 + 861 Protein_992 copper homeostasis membrane protein CopD -
I6K17_RS05665 1021319..1021660 + 342 WP_000976472.1 YebY family protein -
- 1021690..1021921 - 232 - - Antitoxin
- 1021818..1021920 + 103 - - Toxin
I6K17_RS05670 1022052..1023128 - 1077 WP_204608769.1 phage integrase Arm DNA-binding domain-containing protein -
I6K17_RS05675 1023094..1023375 - 282 WP_001311878.1 excisionase -
I6K17_RS05680 1023482..1023670 - 189 WP_204608772.1 DUF1187 family protein -
- 1023486..1023664 + 179 NuclAT_0 - -
- 1023486..1023664 + 179 NuclAT_0 - -
- 1023486..1023664 + 179 NuclAT_0 - -
- 1023486..1023664 + 179 NuclAT_0 - -
I6K17_RS05685 1023663..1023857 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
I6K17_RS05690 1023914..1024723 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1016188..1081641 65453


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192932 NZ_CP070071:1021818-1021920 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT192932 NZ_CP070071:c1021921-1021690 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References