Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 325870..326015 Replicon chromosome
Accession NZ_CP070046
Organism Klebsiella pneumoniae strain FDAARGOS_1319

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 325877..325979 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 325870..326015 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K49_RS01605 321401..322834 + 1434 WP_065811950.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K49_RS01610 322950..323189 + 240 WP_002911393.1 YebV family protein -
I6K49_RS01615 323287..323478 + 192 WP_002911395.1 YebW family protein -
I6K49_RS01620 323475..324128 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
I6K49_RS01625 324285..325253 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K49_RS01630 325358..325501 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 325870..326015 + 146 - - Antitoxin
- 325877..325979 - 103 - - Toxin
I6K49_RS01635 326138..326476 - 339 WP_002911404.1 YebY family protein -
I6K49_RS01640 326493..327362 - 870 WP_004891049.1 copper homeostasis membrane protein CopD -
I6K49_RS01645 327366..327740 - 375 WP_048279882.1 CopC domain-containing protein YobA -
I6K49_RS01650 327853..328083 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K49_RS01655 328162..328821 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K49_RS01660 328825..330885 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192802 NZ_CP070046:c325979-325877 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192802 NZ_CP070046:325870-326015 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References