Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 424795..425063 Replicon chromosome
Accession NZ_CP070041
Organism Escherichia coli strain FDAARGOS_1293

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 424923..425025 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 424795..425063 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K23_RS01945 420094..420756 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6K23_RS01950 420780..421436 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
I6K23_RS01955 421539..421769 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6K23_RS01960 422016..423185 + 1170 Protein_384 IS3-like element ISEc52 family transposase -
I6K23_RS01965 423179..423535 + 357 WP_204628207.1 CopC domain-containing protein YobA -
I6K23_RS01970 423539..424411 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
I6K23_RS01975 424424..424765 + 342 WP_000984819.1 YebY family protein -
- 424795..425063 - 269 - - Antitoxin
- 424923..425025 + 103 - - Toxin
I6K23_RS01980 425160..425816 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
I6K23_RS01985 425817..426008 - 192 WP_001317886.1 YebW family protein -
I6K23_RS01990 426113..426349 - 237 WP_001295499.1 YebV family protein -
I6K23_RS01995 426467..427906 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 418037..440903 22866


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192743 NZ_CP070041:424923-425025 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT192743 NZ_CP070041:c425063-424795 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References