Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4882608..4882753 Replicon chromosome
Accession NZ_CP070037
Organism Klebsiella pneumoniae strain FDAARGOS_1322

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4882644..4882746 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4882608..4882753 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K52_RS23680 4877738..4879798 + 2061 WP_004151449.1 oligopeptidase B -
I6K52_RS23685 4879802..4880461 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6K52_RS23690 4880540..4880770 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K52_RS23695 4880883..4881257 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K52_RS23700 4881261..4882130 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I6K52_RS23705 4882147..4882485 + 339 WP_002911404.1 YebY family protein -
- 4882608..4882753 - 146 - - Antitoxin
- 4882644..4882746 + 103 - - Toxin
I6K52_RS23710 4883121..4883264 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K52_RS23715 4883369..4884337 - 969 WP_014907334.1 VirK/YbjX family protein -
I6K52_RS23720 4884494..4885147 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
I6K52_RS23725 4885144..4885335 - 192 WP_002911395.1 YebW family protein -
I6K52_RS23730 4885433..4885672 - 240 WP_002911393.1 YebV family protein -
I6K52_RS23735 4885788..4887221 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192731 NZ_CP070037:4882644-4882746 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192731 NZ_CP070037:c4882753-4882608 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References