Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 34140..34285 Replicon chromosome
Accession NZ_CP070015
Organism Klebsiella pneumoniae strain FDAARGOS_1309

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 34147..34249 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 34140..34285 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K39_RS00145 29671..31104 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K39_RS00150 31220..31459 + 240 WP_002911393.1 YebV family protein -
I6K39_RS00155 31557..31748 + 192 WP_002911395.1 YebW family protein -
I6K39_RS00160 31745..32398 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
I6K39_RS00165 32555..33523 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K39_RS00170 33628..33771 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 34140..34285 + 146 - - Antitoxin
- 34147..34249 - 103 - - Toxin
I6K39_RS00175 34408..34746 - 339 WP_002911404.1 YebY family protein -
I6K39_RS00180 34763..35632 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
I6K39_RS00185 35636..36010 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K39_RS00190 36123..36353 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K39_RS00195 36432..37091 + 660 WP_020324964.1 exodeoxyribonuclease X -
I6K39_RS00200 37095..39155 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192660 NZ_CP070015:c34249-34147 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192660 NZ_CP070015:34140-34285 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References