Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4476409..4476677 Replicon chromosome
Accession NZ_CP069996
Organism Escherichia coli strain FDAARGOS_1300

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4476537..4476639 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4476409..4476677 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K30_RS21720 4472963..4473625 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6K30_RS21725 4473648..4474304 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
I6K30_RS21730 4474406..4474636 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6K30_RS21735 4474775..4475149 + 375 WP_000168747.1 CopC domain-containing protein YobA -
I6K30_RS21740 4475153..4476025 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
I6K30_RS21745 4476038..4476379 + 342 WP_000984819.1 YebY family protein -
- 4476409..4476677 - 269 - - Antitoxin
- 4476537..4476639 + 103 - - Toxin
I6K30_RS21750 4476774..4477430 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
I6K30_RS21755 4477431..4477622 - 192 WP_001296140.1 YebW family protein -
I6K30_RS21760 4477727..4477963 - 237 WP_001295499.1 YebV family protein -
I6K30_RS21765 4478081..4479520 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192602 NZ_CP069996:4476537-4476639 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT192602 NZ_CP069996:c4476677-4476409 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References