Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2412576..2412721 | Replicon | chromosome |
| Accession | NZ_CP069994 | ||
| Organism | Klebsiella pneumoniae strain FDAARGOS_1321 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2412583..2412685 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2412576..2412721 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K51_RS11765 | 2408108..2409541 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| I6K51_RS11770 | 2409657..2409896 | + | 240 | WP_002911393.1 | YebV family protein | - |
| I6K51_RS11775 | 2409994..2410185 | + | 192 | WP_002911395.1 | YebW family protein | - |
| I6K51_RS11780 | 2410182..2410835 | - | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| I6K51_RS11785 | 2410992..2411960 | + | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| I6K51_RS11790 | 2412065..2412208 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 2412576..2412721 | + | 146 | - | - | Antitoxin |
| - | 2412583..2412685 | - | 103 | - | - | Toxin |
| I6K51_RS11795 | 2412844..2413182 | - | 339 | WP_002911404.1 | YebY family protein | - |
| I6K51_RS11800 | 2413199..2414068 | - | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| I6K51_RS11805 | 2414072..2414446 | - | 375 | WP_020316569.1 | CopC domain-containing protein YobA | - |
| I6K51_RS11810 | 2414559..2414789 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| I6K51_RS11815 | 2414868..2415527 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| I6K51_RS11820 | 2415531..2417591 | - | 2061 | WP_032419805.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T192562 NZ_CP069994:c2412685-2412583 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT192562 NZ_CP069994:2412576-2412721 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT