Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2412576..2412721 Replicon chromosome
Accession NZ_CP069994
Organism Klebsiella pneumoniae strain FDAARGOS_1321

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2412583..2412685 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2412576..2412721 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K51_RS11765 2408108..2409541 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K51_RS11770 2409657..2409896 + 240 WP_002911393.1 YebV family protein -
I6K51_RS11775 2409994..2410185 + 192 WP_002911395.1 YebW family protein -
I6K51_RS11780 2410182..2410835 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
I6K51_RS11785 2410992..2411960 + 969 WP_014907334.1 VirK/YbjX family protein -
I6K51_RS11790 2412065..2412208 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2412576..2412721 + 146 - - Antitoxin
- 2412583..2412685 - 103 - - Toxin
I6K51_RS11795 2412844..2413182 - 339 WP_002911404.1 YebY family protein -
I6K51_RS11800 2413199..2414068 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I6K51_RS11805 2414072..2414446 - 375 WP_020316569.1 CopC domain-containing protein YobA -
I6K51_RS11810 2414559..2414789 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K51_RS11815 2414868..2415527 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K51_RS11820 2415531..2417591 - 2061 WP_032419805.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192562 NZ_CP069994:c2412685-2412583 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192562 NZ_CP069994:2412576-2412721 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References