Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2342636..2342781 Replicon chromosome
Accession NZ_CP069992
Organism Klebsiella pneumoniae strain FDAARGOS_1329

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2342643..2342745 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2342636..2342781 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K59_RS11550 2338168..2339601 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K59_RS11555 2339717..2339956 + 240 WP_002911393.1 YebV family protein -
I6K59_RS11560 2340054..2340245 + 192 WP_002911395.1 YebW family protein -
I6K59_RS11565 2340242..2340895 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
I6K59_RS11570 2341052..2342020 + 969 WP_162472361.1 VirK/YbjX family protein -
I6K59_RS11575 2342125..2342268 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2342636..2342781 + 146 - - Antitoxin
- 2342643..2342745 - 103 - - Toxin
I6K59_RS11580 2342904..2343242 - 339 WP_002911404.1 YebY family protein -
I6K59_RS11585 2343259..2344128 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I6K59_RS11590 2344132..2344506 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K59_RS11595 2344619..2344849 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K59_RS11600 2344928..2345587 + 660 WP_021440386.1 exodeoxyribonuclease X -
I6K59_RS11605 2345591..2347651 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192542 NZ_CP069992:c2342745-2342643 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192542 NZ_CP069992:2342636-2342781 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References