Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1459080..1459225 Replicon chromosome
Accession NZ_CP069962
Organism Klebsiella pneumoniae strain FDAARGOS_1307

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1459116..1459218 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1459080..1459225 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K37_RS07180 1454210..1456270 + 2061 WP_004151449.1 oligopeptidase B -
I6K37_RS07185 1456274..1456933 - 660 WP_004180433.1 exodeoxyribonuclease X -
I6K37_RS07190 1457012..1457242 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K37_RS07195 1457355..1457729 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K37_RS07200 1457733..1458602 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
I6K37_RS07205 1458619..1458957 + 339 WP_002911404.1 YebY family protein -
- 1459080..1459225 - 146 - - Antitoxin
- 1459116..1459218 + 103 - - Toxin
I6K37_RS07210 1459594..1459737 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K37_RS07215 1459842..1460810 - 969 WP_004151446.1 VirK/YbjX family protein -
I6K37_RS07220 1460967..1461620 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
I6K37_RS07225 1461617..1461808 - 192 WP_002911395.1 YebW family protein -
I6K37_RS07230 1461906..1462145 - 240 WP_002911393.1 YebV family protein -
I6K37_RS07235 1462261..1463694 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192341 NZ_CP069962:1459116-1459218 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192341 NZ_CP069962:c1459225-1459080 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References